ReviewInternational journal of molecular sciences2025
Roles of Selected Bioactive Compounds in Inhibiting the Development and Progression of Cancer-A Review.
Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Synthesis and Cytotoxic Activity Study of Conjugates of N-Acyl Derivatives of 3,5-Bis(benzylidene)-4-piperidones and Phenothiazine.International journal of molecular sciences · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Natural bioactive compounds play an important role in regulating inflammatory processes and mechanisms of carcinogenesis. In view of the growing interest in their therapeutic properties, particularly in the treatment of chronic inflammation, cancer, and related diseases, this study reviews the molecular mechanisms of action of selected groups of compounds, namely polyphenols and carotenoids. The analysis is based on current scientific literature and evidence from in vitro and in vivo studies, with particular attention being paid to their effects on the NF-κB, STAT3, and MAPK regulatory pathways, as well as their role in modulating pro-inflammatory cytokine expression, apoptosis, and oxidative stress. These findings indicate that bioactive compounds represent a promising group of substances with a broad spectrum of biological activity. Nevertheless, their potential in combination therapy and in preventive strategies against cancer and inflammation requires further clinical investigation to clarify their bioavailability, safety, and therapeutic effectiveness.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.