Evidence map›Paper›PMID 41226491›Full record

ArticleInternational journal of molecular sciences2025

Optineurin Shapes Basal and LPS-Induced Transcriptomes in BV2 Microglia.

Sara Cappelli, Josip Peradinovic, Nikolina Mohovic, Purba Mandal, Cristiana Stuani, Alessandra Longo, Jason R Cannon, Priyanka Baloni, Benedetta Leoni, Tamara Krsmanovic and 6 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Sara CappelliInternational Centre for Genetic Engineering and Biotechnology (ICGEB), Padriciano 99, 34149 Trieste, Italy.ORCID 0000-0002-5001-3905
Josip PeradinovicLaboratory for Molecular Immunology, Faculty of Biotechnology and Drug Development, University of Rijeka, R. Matejčić 2, 51000 Rijeka, Croatia.ORCID 0000-0002-7742-7841
Nikolina MohovicLaboratory for Molecular Immunology, Faculty of Biotechnology and Drug Development, University of Rijeka, R. Matejčić 2, 51000 Rijeka, Croatia.ORCID 0000-0001-7744-904X
Purba MandalSchool of Health Sciences, Purdue University, West Lafayette, IN 47907, USA.ORCID 0009-0006-5165-1761
Cristiana StuaniInternational Centre for Genetic Engineering and Biotechnology (ICGEB), Padriciano 99, 34149 Trieste, Italy.
Alessandra LongoInternational Centre for Genetic Engineering and Biotechnology (ICGEB), Padriciano 99, 34149 Trieste, Italy.
Jason R CannonSchool of Health Sciences, Purdue University, West Lafayette, IN 47907, USA.ORCID 0000-0003-1907-4555
Priyanka BaloniSchool of Health Sciences, Purdue University, West Lafayette, IN 47907, USA.ORCID 0000-0002-3382-4941
Benedetta LeoniMetisox-Cell Networks GmbH, 69120 Heidelberg, Germany.
Tamara KrsmanovicMetisox-Cell Networks GmbH, 69120 Heidelberg, Germany.
Katica StojanovMetisox-Cell Networks GmbH, 69120 Heidelberg, Germany.
Gordana ApicMetisox-Cell Networks GmbH, 69120 Heidelberg, Germany.
Robert B RussellBioQuant, Heidelberg University, 69120 Heidelberg, Germany.ORCID 0000-0002-7213-1398
Maurizio RomanoDepartment of Life Sciences, University of Trieste, Via Licio Giorgieri 5, 34127 Trieste, Italy.ORCID 0000-0002-4820-2897
Emanuele BurattiInternational Centre for Genetic Engineering and Biotechnology (ICGEB), Padriciano 99, 34149 Trieste, Italy.ORCID 0000-0002-1356-9074
Ivana MuniticLaboratory for Molecular Immunology, Faculty of Biotechnology and Drug Development, University of Rijeka, R. Matejčić 2, 51000 Rijeka, Croatia.ORCID 0000-0002-5171-9950

Funding

Croatian Science Foundation DOK-2018-09-7739Croatian Science Foundation DOK-2020-01-8703Croatian Science Foundation IP-2018-01-8563Croatian Science Foundation IP-2024-05-5814SCiLS 861 329
6 · The paper itself

Abstract

The

Indexed as

Cell Cycle ProteinsLipopolysaccharidesMicrogliaTranscription Factor TFIIIATranscriptomeAnimalsCell LineGene Expression ProfilingGene Expression RegulationMembrane Transport ProteinsMiceCell Cycle ProteinsLipopolysaccharidesMembrane Transport ProteinsOptn protein, mouseTranscription Factor TFIIIABV2 microgliaCRISPR-Cas9inflammationinterferon signalingLPSneuroinflammationoptineurinRNA-Seq

Identifiers

PMID41226491
PMCPMC12607547

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.