Evidence map›Paper›PMID 41226579›Full record

ArticleInternational journal of molecular sciences2025

Melatonin at Crossroads with Phytohormones: Interactions Under High Light Stress.

Ivan A Bychkov, Natalia V Kudryakova, Victoria V Shitikova, Victor V Kusnetsov

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ivan A BychkovK.A. Timiryazev Institute of Plant Physiology RAS, 35 Botanicheskaya St., 127276 Moscow, Russia.
Natalia V KudryakovaK.A. Timiryazev Institute of Plant Physiology RAS, 35 Botanicheskaya St., 127276 Moscow, Russia.ORCID 0000-0002-3979-1554
Victoria V ShitikovaK.A. Timiryazev Institute of Plant Physiology RAS, 35 Botanicheskaya St., 127276 Moscow, Russia.ORCID 0009-0004-2457-0646
Victor V KusnetsovK.A. Timiryazev Institute of Plant Physiology RAS, 35 Botanicheskaya St., 127276 Moscow, Russia.ORCID 0000-0003-4979-6137

Funding

Ministry of Science and Higher Education of the Russian Federation 122042700044-6Russian Science Foundation 23-14-00011
6 · The paper itself

Abstract

Melatonin (MT), an antioxidant and growth regulator, interacts with almost all phytohormones, but the molecular mechanisms of these interactions are poorly understood. Using mRNA sequencing (mRNA-seq) technology, we analysed the global regulation of MT-induced expression of genes involved in metabolism, signalling and responses to major phytohormones under prolonged high-intensity light (HL) stress. Plants respond to MT through the activation of auxin and brassinosteroid (BS) response genes, which were identified among the enriched categories of differentially expressed genes (DEGs) with increased expression, and the suppression of abscisic acid and ethylene signalling and response genes, which were among the enriched downregulated categories. MT also suppressed growth-inhibiting genes involved in jasmonic acid (JA) and salicylic acid (SA) signalling and response and activated genes encoding the growth-promoting hormones gibberellins and cytokinins (CKs), which is consistent with the role of MT in stress alleviation. However, the expression of some unique genes, which are positively or negatively modulated by stress, was reinforced by MT treatment, illustrating the extraordinary type of regulation that enhances the action of specific hormone-mediated mechanisms. The study of signal integration between MT and hormones with the involvement of signalling mutants revealed that some interactions are regulated at the transcriptional level and require the activity of relevant signalling pathways. Disruption of

Indexed as

ArabidopsisLightMelatoninPlant Growth RegulatorsStress, PhysiologicalArabidopsis ProteinsGene Expression Regulation, PlantSignal TransductionArabidopsis ProteinsMelatoninPlant Growth RegulatorsArabidopsis thalianahigh light stressmelatoninmRNA sequencingphytohormones

Identifiers

PMID41226579
PMCPMC12607704

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.