Evidence map›Paper›PMID 41226594›Full record

ArticleInternational journal of molecular sciences2025

Differential Expression of Circular RNAs in Rat Brain Regions with Various Degrees of Damage After Ischemia-Reperfusion.

Ivan V Mozgovoy, Ekaterina V Tsareva, Alina E Denisova, Vasily V Stavchansky, Leonid V Gubsky, Lyudmila V Dergunova, Svetlana A Limborska, Ivan B Filippenkov

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In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ivan V MozgovoyLaboratory of Human Molecular Genetics, National Research Center "Kurchatov Institute", Kurchatov Sq. 2, Moscow 123182, Russia.ORCID 0009-0008-3284-1249
Ekaterina V TsarevaLaboratory of Human Molecular Genetics, National Research Center "Kurchatov Institute", Kurchatov Sq. 2, Moscow 123182, Russia.
Alina E DenisovaDepartment of Neurology, Neurosurgery and Medical Genetics, Pirogov Russian National Research Medical University, Ostrovitianov Str. 1, Moscow 117997, Russia.
Vasily V StavchanskyLaboratory of Human Molecular Genetics, National Research Center "Kurchatov Institute", Kurchatov Sq. 2, Moscow 123182, Russia.
Leonid V GubskyDepartment of Neurology, Neurosurgery and Medical Genetics, Pirogov Russian National Research Medical University, Ostrovitianov Str. 1, Moscow 117997, Russia.
Lyudmila V DergunovaLaboratory of Human Molecular Genetics, National Research Center "Kurchatov Institute", Kurchatov Sq. 2, Moscow 123182, Russia.ORCID 0000-0003-2789-2419
Svetlana A LimborskaLaboratory of Human Molecular Genetics, National Research Center "Kurchatov Institute", Kurchatov Sq. 2, Moscow 123182, Russia.
Ivan B FilippenkovLaboratory of Human Molecular Genetics, National Research Center "Kurchatov Institute", Kurchatov Sq. 2, Moscow 123182, Russia.ORCID 0000-0002-6964-3405

Funding

NRC "Kurchatov Institute" 5f.5.9Russian Science Foundation 25-14-00047
6 · The paper itself

Abstract

Circular RNAs (circRNAs) are non-coding RNAs that can significantly influence the regulation of gene expression in health and disease, including ischemic stroke. We identified 597 differentially expressed circRNAs (DECs) (fold change > 1.5;

Indexed as

BrainBrain IschemiaReperfusion InjuryRNA, CircularAnimalsFrontal LobeGene Expression ProfilingGene Expression RegulationGene Regulatory NetworksMaleMicroRNAsRatsRats, Sprague-DawleyRNA, MessengerMicroRNAsRNA, CircularRNA, MessengercircRNA-microRNA-mRNA networkcircRNAsgene expressionischemic strokemicroRNAsregulatory axesRNA-Seq

Identifiers

PMID41226594
PMCPMC12608004

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.