Evidence mapPaperPMID 41226618Full record

ArticleInternational journal of molecular sciences2025

Sustainable Valorization of Grape Pomace in Sheep Through Systemic Health, Metabolic Safety, Milk and Meat Quality.

Gabriella Guelfi, Piermario Mangili, Francesca Mercati, David Ranucci, Silvia Crotti, Muhammad Tuseef, Gianluca Veneziani, Vicente Francisco Ratto, Camilla Capaccia, Francesco Ciancabilla and 2 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Gabriella GuelfiDepartment of Veterinary Medicine, University of Perugia, 06126 Perugia, Italy.ORCID 0000-0003-3695-9275
Piermario MangiliIstituto Zooprofilattico Sperimentale Umbria e Marche "Togo Rosati", 06126 Perugia, Italy.
Francesca MercatiDepartment of Veterinary Medicine, University of Perugia, 06126 Perugia, Italy.ORCID 0000-0002-8799-1200
David RanucciDepartment of Veterinary Medicine, University of Perugia, 06126 Perugia, Italy.ORCID 0000-0002-5919-7122
Silvia CrottiIstituto Zooprofilattico Sperimentale Umbria e Marche "Togo Rosati", 06126 Perugia, Italy.ORCID 0000-0002-4798-1964
Muhammad TuseefDepartment of Science, University of Basilicata, 85100 Potenza, Italy.
Gianluca VenezianiDepartment of Agricultural, Food and Environmental Sciences, University of Perugia, 06126 Perugia, Italy.ORCID 0000-0003-3566-5603
Vicente Francisco RattoDepartment of Veterinary Medicine, University of Perugia, 06126 Perugia, Italy.
Camilla CapacciaDepartment of Veterinary Medicine, University of Perugia, 06126 Perugia, Italy.ORCID 0000-0002-1040-6245
Francesco CiancabillaDepartment of Veterinary Medicine, University of Perugia, 06126 Perugia, Italy.
Margherita MaranesiDepartment of Veterinary Medicine, University of Perugia, 06126 Perugia, Italy.ORCID 0000-0002-1727-4118
Cecilia Dall'AglioDepartment of Veterinary Medicine, University of Perugia, 06126 Perugia, Italy.ORCID 0000-0001-6451-3751

Funding

Fondazione Cassa di Risparmio di Perugia, Grant "Benessere animale ed economia circolare: lo studio di molecole correlate al metabolismo energetico finalizzate al sostegno delle attività vitivinicole e pastorali del territorio umbro" 2022.0395
6 · The paper itself

Abstract

Grape pomace (GP), a by-product of winemaking, is rich in polyphenols and fiber, making it a promising and sustainable feed supplement for ruminants. This study evaluated the safety and productive impact of a 5% GP-supplemented diet (GP5) including non-lactating end-cycle (EC) ewes regularly destined for slaughter and human consumption, and lactating (LAC) ewes, over a 30-day period. Control (CTRL) animals received a standard pellet diet with no GP inclusion. Sampling was performed at four time points (T0, T10, T20, and T30), corresponding to days 0, 10, 20, and 30 of the experimental period. The study assessed clinical status, hematology/biochemistry (T0 and T30), milk composition (T0, T10, T20, and T30), meat quality traits and oxidative stability in EC ewes (T30). Since no significant differences were observed in the CTRL animals, the effects were evaluated within the GP5 group by comparing T0 vs. T30. Meat quality was assessed by comparing EC-GP5 to CTRL at T30. The GP extract showed a high total phenolic content (254.02 ± 20.39 mg GAE/g DW). No clinical or hematological alterations were observed, and most values remained within physiological ranges. Biochemical analysis revealed significant increases in albumin, bilirubin, creatinine, and triglycerides (

Indexed as

Animal FeedMeatMilkVitisAnimalsDietDietary SupplementsFemaleLactationSheepcircular economyfeed supplementgrape marcmeat qualitymilk compositionpolyphenolsruminantssustainabilitysystemic health

Identifiers

PMID41226618
PMCPMC12609406

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.