Evidence map›Paper›PMID 41226643›Full record

ArticleInternational journal of molecular sciences2025

Artificial Intelligence Reveals Nature: Functional Parallels Between a Designed and a Natural Peptide.

Jiashu Wang, Thomas David Daniel Kazmirchuk, Maryam Hajikarimlou, Mustafa Al-Gafari, Sarah Takallou, Houman Moteshareie, Frank Dehne, Bahram Samanfar, Mohan Babu, Taha Azad and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jiashu WangOttawa Institute of Systems Biology, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.
Thomas David Daniel KazmirchukOttawa Institute of Systems Biology, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.
Maryam HajikarimlouOttawa Institute of Systems Biology, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.ORCID 0000-0003-0762-3465
Mustafa Al-GafariOttawa Institute of Systems Biology, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.ORCID 0000-0002-3877-6707
Sarah TakallouOttawa Institute of Systems Biology, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.ORCID 0009-0009-8349-3771
Houman MoteshareieOttawa Institute of Systems Biology, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.
Frank DehneSchool of Computer Science, Faculty of Science, Carleton University, Ottawa, ON K1S 5B6, Canada.
Bahram SamanfarDepartment of Biology, Faculty of Science, Carleton University, Ottawa, ON K1S 5B6, Canada.ORCID 0000-0001-6625-2153
Mohan BabuDepartment of Biochemistry, University of Regina, Regina, SK S4S 0A2, Canada.
Taha AzadDepartment of Microbiology and Infectiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke Cancer Research Institute, Université de Sherbrooke, Sherbrooke, QC J1E 4K8, Canada.
Ashkan GolshaniOttawa Institute of Systems Biology, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.

Funding

Natural Sciences and Engineering Research Council of Canada 123456
6 · The paper itself

Abstract

Natural peptides derived from plants have been an important source of medical substances for several decades. Due to their mechanism of action, chemical potential, and favourable side effect profile, these peptides represent a safer alternative to synthetic pharmaceutical treatments. In this study, we report the discovery of a natural peptide derived from the

Indexed as

Artificial IntelligencePeptidesSpike Glycoprotein, CoronavirusAngiotensin-Converting Enzyme 2Brassica napusCOVID-19HumansMolecular Docking SimulationPlant ProteinsProtein BindingSARS-CoV-2ACE2 protein, humanAngiotensin-Converting Enzyme 2PeptidesPlant ProteinsSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2AI-assisted drug designartificial intelligencenatural peptidesSARS-CoV-2synthetic peptidestheranostic peptides

Identifiers

PMID41226643
PMCPMC12610437

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.