Evidence mapPaperPMID 41226667Full record

ArticleInternational journal of molecular sciences2025

Impact of Isoquinoline Alkaloids on the Intestinal Barrier in a Colonic Model of

Anna Duda-Madej, Przemysław Gagat, Jerzy Wiśniewski, Szymon Viscardi, Paweł Krzyżek

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anna Duda-MadejDepartment of Microbiology, Faculty of Medicine, Wroclaw Medical University, Chałubińskiego 4, 50-368 Wroclaw, Poland.ORCID 0000-0001-8559-1695
Przemysław GagatFaculty of Biotechnology, University of Wroclaw, Fryderyka Joliot-Curie 14a, 50-137 Wroclaw, Poland.ORCID 0000-0001-9077-439X
Jerzy WiśniewskiDepartment of Biochemistry, Molecular Biology and Biotechnology, Faculty of Chemistry, Wroclaw University of Science and Technology, 50-370 Wroclaw, Poland.ORCID 0000-0003-2831-7643
Szymon ViscardiFaculty of Medicine, Wroclaw Medical University, Ludwika Pasteura 1, 50-367 Wroclaw, Poland.ORCID 0009-0007-3668-6891
Paweł KrzyżekDepartment of Microbiology, Faculty of Medicine, Wroclaw Medical University, Chałubińskiego 4, 50-368 Wroclaw, Poland.ORCID 0000-0002-3117-8894

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phytotherapy is a growing field of modern medicine, offering natural alternatives with multidirectional pharmacological effects. Among plant-derived bioactive compounds, isoquinoline alkaloids exhibit antioxidant, anti-inflammatory, and antimicrobial properties. Our in vitro model of campylobacteriosis confirmed that berberine reduces pathological changes in colonocytes not only through its direct antibacterial (minimum inhibitory concentration for pure berberine against

Indexed as

AlkaloidsAnti-Bacterial AgentsBerberineCampylobacter InfectionsCampylobacter jejuniColonIntestinal MucosaIsoquinolinesBiofilmsHumansMicrobial Sensitivity TestsAlkaloidsAnti-Bacterial AgentsBerberineIsoquinolinesberberinebiofilmsCampylobacter jejuni infectionschelerythrineintestinal barriersanguinarine

Identifiers

PMID41226667
PMCPMC12609152

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.