Evidence map›Paper›PMID 41226671›Full record

ArticleInternational journal of molecular sciences2025

Small RNA-Seq Reveals the Effect of Formaldehyde Treatment on Chicken Embryo Liver microRNA Profiles.

Saffet Teber, Mustafa Özdemir, Ghulam Asghar Sajid, Selma Büyükkılıç Beyzi, Mehmet Kizilaslan, Yunus Arzık, Servet Yalçın, Stephen N White, Mehmet Ulas Cinar

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Saffet TeberDepartment of Animal Science, Faculty of Agriculture, Erciyes University, 38280 Kayseri, Türkiye.
Mustafa ÖzdemirDepartment of Animal Science, Faculty of Agriculture, Erciyes University, 38280 Kayseri, Türkiye.ORCID 0000-0001-6160-2484
Ghulam Asghar SajidDepartment of Animal Science, Faculty of Agriculture, Erciyes University, 38280 Kayseri, Türkiye.ORCID 0000-0003-4445-9457
Selma Büyükkılıç BeyziDepartment of Animal Science, Faculty of Agriculture, Erciyes University, 38280 Kayseri, Türkiye.ORCID 0000-0002-4622-0645
Mehmet KizilaslanDepartment of Animal and Dairy Sciences, University of Wisconsin-Madison, Madison, WI 53706, USA.ORCID 0000-0001-6305-8742
Yunus ArzıkDepartment of Animal Science, Faculty of Veterinary Medicine, Aksaray University, 68100 Aksaray, Türkiye.ORCID 0000-0002-3068-8155
Servet YalçınDepartment of Animal Science, Faculty of Agriculture, Ege University, 35100 İzmir, Türkiye.
Stephen N WhitePoultry Microbiological Safety & Processing Research, United States National Poultry Research Center, United States Department of Agriculture-Agricultural Research Service, Athens, GA 30605, USA.ORCID 0000-0001-9255-6054
Mehmet Ulas CinarDepartment of Animal Science, Faculty of Agriculture, Erciyes University, 38280 Kayseri, Türkiye.ORCID 0000-0001-5894-5072

Funding

Erciyes University FOA-2023-12802
6 · The paper itself

Abstract

Formaldehyde (FA) is commonly used for hatchery disinfection, where it reduces microbial growth, ensures successful egg hatch and enhances healthy production, but its specific effects on embryonic development remain unclear. MicroRNAs (miRNAs) regulate gene expression post-transcriptionally and may mediate FA-induced transcriptional responses. Here, we investigated the impact of FA treatment on miRNA profiles in chicken embryo liver. Small RNA-seq libraries were constructed and sequenced using the Illumina NextSeq platform. Reads were trimmed and quantified using miRDeep2 version 2.0.0.3. Differential expression analysis was performed with DESeq2 (

Indexed as

FormaldehydeLiverMicroRNAsTranscriptomeAnimalsChick EmbryoChickensGene Expression ProfilingGene Expression Regulation, DevelopmentalRNA-SeqFormaldehydeMicroRNAschicken embryoexpression profileformaldehydeGallus gallusmiRNA

Identifiers

PMID41226671
PMCPMC12609791

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.