ArticleInternational journal of molecular sciences2025
Biochemical Effects of Natural and Nanoparticle Fish and Algal Oils in Gilt Pregnancy Diets on Base Excision Repair Enzymes in Newborn Piglets-Socioeconomic Implications for Regional Pig Farming-Preliminary Results.
Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Maternal Omega-3 PUFA Supplementation and Mitochondrial Function in a Newborn Piglet Model: A Preliminary Investigation.International journal of molecular sciences · 2026Article
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Authors and funding
7 authors.
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Abstract
Base excision repair (BER) is an important mechanism for maintaining genomic integrity and preventing DNA damage and mutations induced by oxidative stress. This study aimed to examine the relationship between oxidative stress and BER activity in newborn piglets by supplementing their mothers' diets during pregnancy with long-chain n-3 polyunsaturated fatty acids (PUFAs) from algal and fish oils, provided either in natural form or as nanoparticles. BER enzyme activity was assessed using a nicking assay, and their gene expression levels by RT-qPCR in the livers of pregnant gilts and their offspring. Preliminary results indicated that maternal supplementation with oils rich in long-chain n-3 PUFAs significantly reduced (by 32%) BER capacity in the livers of their offspring. A corresponding decrease in mRNA expression of BER genes (
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