Evidence map›Paper›PMID 41226823›Full record

ReviewInternational journal of molecular sciences2025

Update on Nicotinamide and Its Application in the Management of Glaucoma.

Ta-Hung Chiu, Shih-Heng Hung, Chiao-Hsin Lan, Wei-Ting Yen, Da-Wen Lu

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ta-Hung ChiuDepartment of General Medicine, Tri-Service General Hospital, National Defense Medical University, Taipei 114202, Taiwan.ORCID 0009-0007-8263-9607
Shih-Heng HungDepartment of Ophthalmology, Show Chwan Memorial Hospital, Changhua 500, Taiwan.
Chiao-Hsin LanDepartment of Medical Education, National Taiwan University Hospital, Taipei 100225, Taiwan.ORCID 0000-0001-8134-3619
Wei-Ting YenDepartment of Ophthalmology, College of Medicine, National Defense Medical University, Taipei 114202, Taiwan.ORCID 0000-0002-1473-2531
Da-Wen LuDepartment of Ophthalmology, College of Medicine, National Defense Medical University, Taipei 114202, Taiwan.

Funding

Tri-Service General Hospital Research Foundation TSGH-E-114265
6 · The paper itself

Abstract

Glaucoma continues to be a primary contributor to permanent vision loss worldwide, frequently advancing even when intraocular pressure management is clinically adequate. Accumulating research emphasizes the metabolic susceptibility of retinal ganglion cells (RGCs), specifically concerning the progressive depletion of nicotinamide adenine dinucleotide (NAD

Indexed as

GlaucomaNeuroprotective AgentsNiacinamideAnimalsHumansRetinal Ganglion CellsNeuroprotective AgentsNiacinamideglaucomaNAD+ metabolismneuroprotectionnicotinamideretinal ganglion cellssalvage pathwayvitamin B3

Identifiers

PMID41226823
PMCPMC12609723

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.