Evidence map›Paper›PMID 41227287›Full record

ArticleJournal of clinical medicine2025

Personalized Prediction of Clozapine Treatment Response Using Therapeutic Drug Monitoring Data in Japanese Patients with Treatment-Resistant Schizophrenia.

Tatsuo Nakahara, Yukiko Harada, Naho Nakayama, Kijiro Hashimoto, Naoya Kida, Toshiaki Onitsuka, Hiroo Noda, Kenji Murasugi, Yoshihiro Takimoto, Wataru Omori and 5 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Tatsuo NakaharaNational Hospital Organization, Hizen Psychiatric Center, Saga 842-0192, Japan.ORCID 0000-0002-9090-4876
Yukiko HaradaNational Hospital Organization, Hizen Psychiatric Center, Saga 842-0192, Japan.ORCID 0009-0008-2671-1616
Naho NakayamaNational Hospital Organization, Hizen Psychiatric Center, Saga 842-0192, Japan.
Kijiro HashimotoNational Hospital Organization, Hizen Psychiatric Center, Saga 842-0192, Japan.
Naoya KidaNational Hospital Organization, Ryukyu Hospital, Okinawa 904-1201, Japan.
Toshiaki OnitsukaNational Hospital Organization, Sakakibara Hospital, Mie 514-1292, Japan.ORCID 0000-0001-6583-6405
Hiroo NodaNational Hospital Organization, Saigata Medical Center, Niigata 949-3193, Japan.
Kenji MurasugiNational Hospital Organization, Komoro Kogen Hospital, Nagano 384-8540, Japan.
Yoshihiro TakimotoNational Hospital Organization, Yamato Psychiatric Center, Nara 639-1042, Japan.
Wataru OmoriNational Hospital Organization, Department of Psychiatry, Kure Medical Center and Chugoku Cancer Center, Hiroshima 737-0023, Japan.
Tsuruhei SukegawaNational Hospital Organization, Tottori Medical Center, Tottori 689-0203, Japan.
Jun ShiraishiNational Hospital Organization, Hokuriku Hospital, Toyama 939-1893, Japan.
Kouji TanakaNational Hospital Organization, Kikuchi National Hospital, Kumamoto 861-1116, Japan.
Hitoshi MaesatoNational Hospital Organization, Ryukyu Hospital, Okinawa 904-1201, Japan.ORCID 0000-0002-3586-6432
Takefumi UenoNational Hospital Organization, Hizen Psychiatric Center, Saga 842-0192, Japan.ORCID 0000-0003-2905-9340

Funding

Grants-in-Aid for Scientific Research on Health, Labour and Welfare 20GC1017
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

clozapineclozapine N-oxidenorclozapinepersonalized medicinerandom forest (RF)therapeutic drug monitoring (TDM)treatment-resistant schizophrenia (TRS)

Identifiers

PMID41227287
PMCPMC12610035

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.