Evidence mapPaperPMID 41227372Full record

ReviewCells2025

Therapeutic and Clinical Potential of Adipose-Derived Stem Cell Secretome for Skin Regeneration.

Anna Sendera, Hubert Kubis, Anna Pałka, Agnieszka Banaś-Ząbczyk

Abstract readReview
In one paragraph

Review in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anna SenderaDepartment of Medical Biology, Faculty of Medicine, Collegium Medicum, University of Rzeszów, al. Tadeusza Rejtana 16C, 35-959 Rzeszów, Poland.ORCID 0000-0001-5288-0845
Hubert KubisLaboratory of Diagnostic and Clinical Epigenetics, Faculty of Medicine, Collegium Medicum, University of Rzeszów, al. Tadeusza Rejtana 16C, 35-959 Rzeszów, Poland.ORCID 0009-0002-7309-1233
Anna PałkaDepartment of Medical Biology, Faculty of Medicine, Collegium Medicum, University of Rzeszów, al. Tadeusza Rejtana 16C, 35-959 Rzeszów, Poland.ORCID 0009-0007-4421-3656
Agnieszka Banaś-ZąbczykDepartment of Medical Biology, Faculty of Medicine, Collegium Medicum, University of Rzeszów, al. Tadeusza Rejtana 16C, 35-959 Rzeszów, Poland.ORCID 0000-0001-7128-861X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adipose-derived stem cells (AT-MSCs) exhibit great potential for application in stem cell therapy, primarily due to their unique pro-regenerative capabilities, which include supporting skin regeneration. AT-MSCs secrete a variety of biomolecules with immunomodulatory, re-epithelializing, antifibrotic, antiapoptotic, proangiogenic, and neurotrophic activity as well as the ability to promote proliferation and migration of skin cells. Recently, therapy using AT-MSC secretome alone has garnered increasing attention due to its potentially safer and more effective application ability than the use of whole AT-MSCs. This review provides a comprehensive summary of the current state of knowledge regarding the potential use of AT-MSC secretome as a promising cell-free therapeutic strategy for wound healing, alopecia, skin rejuvenation, and skin inflammatory diseases. We critically analyze and discuss findings from

Indexed as

Adipose TissueMesenchymal Stem CellsRegenerationSecretomeSkinStem CellsAnimalsHumansWound Healingadipose-derived stem cellsalopecia treatmentAT-MSCsconditioned mediaexosomesextracellular vesiclespreconditioningskin aging preventionstem cell therapywound healing

Identifiers

PMID41227372
PMCPMC12610433

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.