Evidence mapPaperPMID 41227377Full record

ArticleCells2025

Alterations in Circulating T-Cell Subsets with Gut-Homing/Residency Phenotypes Associated with HIV-1 Status and Subclinical Atherosclerosis.

Etiene Moreira Gabriel, Jonathan Dias, Abdelali Filali-Mouhim, Ramon Edwin Caballero, Tomas Raul Wiche Salinas, Manon Nayrac, Carl Chartrand-Lefebvre, Jean-Pierre Routy, Madeleine Durand, Mohamed El-Far and 2 more

Abstract read
In one paragraph

Article in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Etiene Moreira GabrielDépartement de Microbiologie, Infectiologie et Immunologie, Faculté de Médecine, Université de Montréal, Montreal, QC H2C 3J7, Canada.
Jonathan DiasDépartement de Microbiologie, Infectiologie et Immunologie, Faculté de Médecine, Université de Montréal, Montreal, QC H2C 3J7, Canada.ORCID 0000-0002-7842-0115
Abdelali Filali-MouhimCentre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), 900 Rue Saint-Denis, Tour Viger R, Room R09.416, Montreal, QC H2X 0A9, Canada.
Ramon Edwin CaballeroCentre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), 900 Rue Saint-Denis, Tour Viger R, Room R09.416, Montreal, QC H2X 0A9, Canada.
Tomas Raul Wiche SalinasDépartement de Microbiologie, Infectiologie et Immunologie, Faculté de Médecine, Université de Montréal, Montreal, QC H2C 3J7, Canada.
Manon NayracCentre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), 900 Rue Saint-Denis, Tour Viger R, Room R09.416, Montreal, QC H2X 0A9, Canada.ORCID 0000-0001-5717-6232
Carl Chartrand-LefebvreCentre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), 900 Rue Saint-Denis, Tour Viger R, Room R09.416, Montreal, QC H2X 0A9, Canada.
Jean-Pierre RoutyChronic Viral Illness Service, Division of Hematology, Research Institute, Health Centre, Glen Site, McGill University, Montreal, QC H4A 3J1, Canada.ORCID 0000-0001-9897-7589
Madeleine DurandCentre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), 900 Rue Saint-Denis, Tour Viger R, Room R09.416, Montreal, QC H2X 0A9, Canada.
Mohamed El-FarCentre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), 900 Rue Saint-Denis, Tour Viger R, Room R09.416, Montreal, QC H2X 0A9, Canada.ORCID 0000-0002-6458-4207
Cécile TremblayDépartement de Microbiologie, Infectiologie et Immunologie, Faculté de Médecine, Université de Montréal, Montreal, QC H2C 3J7, Canada.ORCID 0000-0002-3440-3436
Petronela AncutaDépartement de Microbiologie, Infectiologie et Immunologie, Faculté de Médecine, Université de Montréal, Montreal, QC H2C 3J7, Canada.ORCID 0000-0003-1922-5640

Funding

Role of IL-32 as a predictor and mediator of Premature Aging Phenotypes(PAP) in HIV infection.R01AG054324 · CENTRE HOSPITALIER DE L'UNIVERSITE DE MONTREAL (UNIVERSITY OF MONTREAL HOSPITAL) · 2025 to 2025
$829k
CIHR PJT-153052CIHR PJT-178127NIA NIH HHS R01 AG054324NIH HHS R01AG054324
6 · The paper itself

Abstract

Antiretroviral therapy (ART) controls HIV-1 replication in people with HIV-1 (PWH), but intestinal integrity impairment persists and fuels microbial translocation and chronic immune activation, thus heightening the cardiovascular disease (CVD) risk. Here, we sought to identify novel immunological correlates of the HIV and CVD status in ART-treated PWH (HIV

Indexed as

AtherosclerosisHIV-1HIV InfectionsT-Lymphocyte SubsetsAdultAgedFemaleHumansMaleMiddle AgedPhenotypeARTchemokine receptorsCVDgut-homing adhesion moleculesHIV-1integrinsintraepithelial lymphocytesT-cells

Identifiers

PMID41227377
PMCPMC12607611

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.