Evidence map›Paper›PMID 41227628›Full record

ReviewFoods (Basel, Switzerland)2025

Harnessing Edible Insect Bioactives for Gut Health: A Comprehensive Review on Chitin-Derived Prebiotics and Peptidomic Insights from the Black Soldier Fly.

Thamer Alhasyani, Tarek Ebeid, Mohamed Ghonimy, Saif Alharbi, Mohamed F Y Hassan, Abdullah Jarallah, Mohammed Alkhurayji, Ahmed A H Abdellatif, Hassan Barakat

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Influence ofAnimals : an open access journal from MDPI · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Thamer AlhasyaniCentral Laboratories-Poultry Health Laboratory Department, Al-Watania Poultry Company, Buraydah 11475, Saudi Arabia.ORCID 0009-0006-1808-3280
Tarek EbeidDepartment of Animal and Poultry Production, College of Agriculture and Food, Qassim University, Buraydah 51452, Saudi Arabia.
Mohamed GhonimyDepartment of Agricultural and Biosystems Engineering, College of Agriculture and Food, Qassim University, Buraydah 51452, Saudi Arabia.ORCID 0000-0002-4887-3658
Saif AlharbiDepartment of Food Science and Human Nutrition, College of Agriculture and Food, Qassim University, Buraydah 51452, Saudi Arabia.ORCID 0009-0008-5730-4837
Mohamed F Y HassanDepartment of Food Science and Human Nutrition, College of Agriculture and Food, Qassim University, Buraydah 51452, Saudi Arabia.ORCID 0000-0002-6027-3989
Abdullah JarallahDepartment of Food Science and Human Nutrition, College of Agriculture and Food, Qassim University, Buraydah 51452, Saudi Arabia.ORCID 0009-0005-8804-4810
Mohammed AlkhurayjiDepartment of Food Science and Human Nutrition, College of Agriculture and Food, Qassim University, Buraydah 51452, Saudi Arabia.ORCID 0009-0003-1583-5633
Ahmed A H AbdellatifDepartment of Pharmaceutics, College of Pharmacy, Qassim University, Buraydah 51452, Saudi Arabia.ORCID 0000-0002-3186-1896
Hassan BarakatDepartment of Food Science and Human Nutrition, College of Agriculture and Food, Qassim University, Buraydah 51452, Saudi Arabia.ORCID 0000-0002-8358-4835

Funding

Qassim University QU-APC-2025
6 · The paper itself

Abstract

The growing need for sustainable protein and functional food ingredients has made edible insects stand out as a flexible source of bioactives. Black Soldier Fly larva (BSFL) bioactives, such as chitooligosaccharides (COSs) and peptides, present potential benefits for gut health; nevertheless, their molecular pathways, clinical validation, and commercial scalability have yet to be thoroughly investigated. This study systematically analyzes current progress in BSFL bioactive extraction and characterization, emphasizing enzymatic and thermal processing, controlled enzyme development, and integrated supercritical fluid enzymatic pipelines. We assess preclinical and animal research that illustrates prebiotic modulation of

Indexed as

bioactivesblack soldier flyedible insectsfunctional foodsgut healthpeptidomicsprebioticssustainability

Identifiers

PMID41227628
PMCPMC12607316

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.