Evidence map›Paper›PMID 41228370›Full record

ArticleCancers2025

Effects of Metformin on Cancer Survival Among Men Diagnosed with Advanced Prostate Cancer Treated with Androgen-Deprivation Therapy: Emulating a Target Trial.

David S Lopez, Efstathia Polychronopoulou, Omer Abdelgadir, Raymond Greenberg, Lindsay G Cowell, Sarah E Messiah, Yong-Fang Kuo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

David S LopezPeter O'Donnell School of Public Health, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.ORCID 0000-0002-2321-0372
Efstathia PolychronopoulouSchool of Public and Population Health, University of Texas Medical Branch, Galveston, TX 77555, USA.ORCID 0000-0002-6126-6465
Omer AbdelgadirPeter O'Donnell School of Public Health, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.ORCID 0009-0002-6104-0156
Raymond GreenbergPeter O'Donnell School of Public Health, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.ORCID 0000-0002-8858-8632
Lindsay G CowellPeter O'Donnell School of Public Health, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.ORCID 0000-0003-1617-8244
Sarah E MessiahPeter O'Donnell School of Public Health, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.ORCID 0000-0001-6685-2175
Yong-Fang KuoSchool of Public and Population Health, University of Texas Medical Branch, Galveston, TX 77555, USA.ORCID 0000-0003-1927-0927

Funding

UT Southwestern Medical Center Simmons Comprehensive Cancer CenterP30CA142543 · UT SOUTHWESTERN MEDICAL CENTER · 2025 to 2025
$4.4M
The Texas Resource Center on Minority Aging Research (RCMAR)P30AG059301 · UNIVERSITY OF TEXAS MED BR GALVESTON · 2025 to 2025
$663k
Cancer Prevention and Research Institute of Texas (CPRIT) RP210130NCI NIH HHS P30 CA142543NIA NIH HHS P30 AG059301
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

advanced stage prostate cancerandrogen deprivation therapymetforminsurvival outcometarget trial emulation

Identifiers

PMID41228370
PMCPMC12609103

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.