Observational studyNutrients2025
The Impact of Dietary Nutrient Intake on Red Blood Cell Distribution Width-Coefficient of Variation in Pregnant Women: A Cross-Sectional Observational Pilot Study.
Observational study in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
objectivesDietary intake during pregnancy influences hematological parameters, reflecting nutritional status and potentially affecting maternal and fetal outcomes. This cross-sectional pilot study aimed to compare dietary nutrient intake in pregnant women depending on their red cell distribution width-coefficient of variation (RDW-CV).
methodsA total of 31 pregnant women in their third trimester were divided into the following two groups: within reference range RDW-CV (
resultsThe elevated RDW-CV group had a significantly lower level of daily energy adequacy. Both groups did not meet recommended intakes for energy, iron, vitamin D. A statistical significance in MCV differences was noted, with lower values in the elevated RDW-CV group, supported by a Cohen's d = 0.82, suggesting early changes in erythrocyte size distribution. The reference range RDW-CV group consumed significantly more zinc, phosphorus, calcium, and vitamin B12, whereas vitamin C intake was higher in the elevated RDW-CV group.
conclusionsPregnant women with an elevated RDW-CV tended to exhibit greater nutritional insufficiencies than those with reference range RDW-CV. Our findings suggest potential associations between hematologic indices (RDW-CV, MCV) and dietary nutrient intake patterns during pregnancy. These preliminary observations are based on a pilot study and warrant confirmation in larger, prospective studies incorporating biochemical markers.
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