Evidence map›Paper›PMID 41228538›Full record

ArticleNutrients2025

Synthetic Food Preservatives Modulate Apoptotic Gene Expression in HepG2 Cells: Divergent Effects of Sodium Benzoate, Potassium Sorbate, and Sodium Metabisulfite.

Márton Pintér, John M Macharia, Orsolya Liza Kövesdi, Nóra Rozmann, Afshin Zand, Katalin Szerb, Tímea Varjas, Bence László Raposa

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Márton PintérDoctoral School of Health Sciences, Faculty of Health Sciences, University of Pécs, Vörösmarty Mihály Str. 4, 7621 Pécs, Hungary.ORCID 0009-0006-8557-4709
John M MachariaDoctoral School of Health Sciences, Faculty of Health Sciences, University of Pécs, Vörösmarty Mihály Str. 4, 7621 Pécs, Hungary.ORCID 0000-0002-7535-9478
Orsolya Liza KövesdiDoctoral School of Health Sciences, Faculty of Health Sciences, University of Pécs, Vörösmarty Mihály Str. 4, 7621 Pécs, Hungary.ORCID 0009-0006-2992-6503
Nóra RozmannInstitute of Emergency Care, Pedagogy of Health and Nursing Sciences, University of Pécs, Vörösmarty Mihály Str. 4, 7621 Pécs, Hungary.ORCID 0000-0002-5621-4935
Afshin ZandDepartment of Public Health Medicine, Medical School, University of Pécs, Vörösmarty Mihály Str. 4, 7621 Pécs, Hungary.ORCID 0000-0001-5656-089X
Katalin SzerbFaculty of Health Sciences, University of Pécs, Vörösmarty Mihály Str. 4, 7621 Pécs, Hungary.
Tímea VarjasDepartment of Public Health Medicine, Medical School, University of Pécs, Vörösmarty Mihály Str. 4, 7621 Pécs, Hungary.ORCID 0000-0002-4950-0669
Bence László RaposaInstitute of Basics of Health Sciences, Midwifery and Health Visiting, Faculty of Health Sciences, University of Pécs, Vörösmarty Mihály Str. 4, 7621 Pécs, Hungary.ORCID 0000-0001-9551-8440

Funding

University of Pecs Institutional Research Support
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ApoptosisFood PreservativesGene ExpressionSodium BenzoateSorbic AcidSulfitesCaspase 3Caspase 8Hep G2 CellsHumansProto-Oncogene Proteins c-bcl-2CASP3 protein, humanCaspase 3Caspase 8Food PreservativesProto-Oncogene Proteins c-bcl-2Sodium Benzoatesodium metabisulfiteSorbic AcidSulfitesadditiveapoptosisepigeneticsgene expressionpotassium sorbatepreservativessodium benzoatesodium metabisulfite

Identifiers

PMID41228538
PMCPMC12609859

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.