ArticleSensors (Basel, Switzerland)2025
Biointegrated Conductive Hydrogel for Real-Time Motion Sensing in Exoskeleton-Assisted Lower-Limb Rehabilitation.
Article in Sensors (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
Chronic lower-extremity wounds in patients undergoing exoskeleton-assisted rehabilitation require materials that can both protect tissue and enable real-time physiological monitoring. Conventional dressings lack dynamic sensing capability, while current conductive hydrogels often compromise either adhesion or electronic performance. Here, we present a biointegrated hydrogel (CPSD) composed of carboxymethyl chitosan (CMCS) and poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) forming the conductive backbone, integrated with dopamine-functionalized sodium alginate (SD); the network is assembled via electrostatic complexation and carbodiimide (EDC/NHS)-mediated covalent crosslinking. The resulting hydrogel exhibits a dense, tissue-conformal porous network with tunable swelling, stable mechanical integrity, and high photothermal conversion efficiency. In vitro assays confirmed potent antioxidant activity, strong antibacterial performance (>90% under near-infrared), and excellent cytocompatibility and hemocompatibility. CPSD shows bulk conductivity ~1.6 S·m
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