ReviewFrontiers in immunology2025
Epstein-Barr virus in thyroid disease: an integrated immunovirological perspective.
Review in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- A System-Level Perspective on Epstein-Barr Virus Persistence: The Partial Lytic Reactivation.International journal of molecular sciences · 2026Review
- Biological Activity of Stilbenoids Against Fungal, Parasitic, and Viral Pathogens.Molecules (Basel, Switzerland) · 2026Review
- Behind the mask of relapsing bimodal encephalitis: herpesvirus 7 and Epstein-Barr virus associated with Hashimoto's encephalopathy: a case report.Frontiers in immunology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Epstein-Barr virus (EBV) is a highly prevalent human herpesvirus capable of establishing lifelong latency in the host. It has garnered increasing attention for its potential pathogenic role in thyroid diseases. This review integrates current evidence linking EBV to a spectrum of thyroid diseases, including Graves' disease, Hashimoto's thyroiditis, thyroid cancer, and other rare subtypes. A key contribution of this work is the synthesized framework that connects viral infection, immune dysregulation, and neoplastic transformation. Unlike previous studies focused on isolated conditions, this review highlights the bridging role of EBV between autoimmunity and thyroid tumorigenesis. In addition, potential EBV-targeted therapeutic strategies are discussed, offering new perspectives for early diagnosis, risk stratification, and personalized management. Overall, this review advances the mechanistic understanding of EBV-associated thyroid diseases and provides a theoretical foundation for future research and clinical interventions.
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Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.