Evidence mapPaperPMID 41229512Full record

ReviewFrontiers in medicine2025

The role of pulmonary rehabilitation in severe asthma: a comprehensive review.

Gabriella Guarnieri, Michela Pozza, Andrea Vianello

Registry-linked trialAbstract readReview
In one paragraph

Review in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07440953 (Effects of Papworth Breathing With or Without Bridge Pose Yoga on Dyspnea, Pulmonary Functions, Chest Expansion and Quality of Life in Asthma Patients), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07440953 nacompletednot on this map

Effects of Papworth Breathing With or Without Bridge Pose Yoga on Dyspnea, Pulmonary Functions, Chest Expansion and Quality of Life in Asthma Patients

TypeinterventionalSponsorRiphah International UniversityRan2024 to 2025Enrolled58ConditionsAsthmaArmsPapeworth Breathing, Pap-worth Breathing + Bridge Pose Yoga
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Gabriella GuarnieriRespiratory Pathophysiology Unit, Department of Cardiac-Thoracic-Vascular Sciences and Public Health, University of Padova, Padova, Italy.
Michela PozzaRespiratory Pathophysiology Unit, Department of Cardiac-Thoracic-Vascular Sciences and Public Health, University of Padova, Padova, Italy.
Andrea VianelloRespiratory Pathophysiology Unit, Department of Cardiac-Thoracic-Vascular Sciences and Public Health, University of Padova, Padova, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Severe asthma remains a major problem despite pharmacological advances. Pulmonary rehabilitation (PR) is established in chronic respiratory disease but its role in severe asthma is unclear. Objectives: Summarise evidence on PR in severe and uncontrolled asthma, describe PR-modalities, and outline implementation and research priorities. Methods: Narrative review of systematic reviews and clinical studies of multidimensional PR programmes and isolated components [aerobic training, inspiratory muscle training (IMT), breathing retraining, neuromuscular electrical stimulation (NMES), telerehabilitation]. Outcomes included asthma control, HRQoL, exercise capacity and healthcare utilisation. Results: Multicomponent PR improves exercise capacity and multiple QoL domains; pooled data show substantial increases in six-minute walk distance. Combined exercise, education and self-management produced clinically meaningful improvements in asthma control and symptoms, notably patients with uncontrolled disease and functional impairment. IMT, NMES and breathing retraining improved inspiratory strength, peripheral muscle function and hyperventilation symptoms. Telerehabilitation expands access but requires attention to digital literacy and adherence. Heterogeneity, small samples and attrition limit generalisability. Conclusion: PR is a promising personalised, multidisciplinary adjunct for severe asthma. Larger phenotype-stratified trials, harmonised outcome sets and implementation research are needed to define candidate selection, optimal dose and cost-effectiveness; embedding PR within severe asthma centres may optimise outcomes and reduce healthcare use.

Indexed as

aerobic trainingbreathing retraininginspiratory muscle trainingmaintenance strategiestelerehabilitation

Identifiers

PMID41229512
PMCPMC12602541

What Socratic holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.