Evidence map›Paper›PMID 41229550›Full record

ArticleInternational journal of general medicine2025

A Retrospective Study to Determine the Preoperative Bilirubin Level for Conducting Preoperative Biliary Drainage to Reduce Pancreaticoduodenectomy Complications.

Xiangyu Chu, Kuinan Tong, Kun Liu, Hongwei Wu, Haonan Li, Jie Liu, Zhonghao Li, Mingcheng Zhang, Wei Guo

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Article in International journal of general medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xiangyu Chu *Department of General Surgery, Beijing Friendship Hospital, Capital Medical University, State Key Laboratory of Digestive Health, National Clinical Research Center for Digestive Diseases, Beijing, 100050, People's Republic of China.
Kuinan Tong *Department of General Surgery, Beijing Friendship Hospital, Capital Medical University, State Key Laboratory of Digestive Health, National Clinical Research Center for Digestive Diseases, Beijing, 100050, People's Republic of China.
Kun LiuDepartment of General Surgery, Beijing Friendship Hospital, Capital Medical University, State Key Laboratory of Digestive Health, National Clinical Research Center for Digestive Diseases, Beijing, 100050, People's Republic of China.
Hongwei WuDepartment of General Surgery, Beijing Friendship Hospital, Capital Medical University, State Key Laboratory of Digestive Health, National Clinical Research Center for Digestive Diseases, Beijing, 100050, People's Republic of China.
Haonan LiDepartment of General Surgery, Beijing Friendship Hospital, Capital Medical University, State Key Laboratory of Digestive Health, National Clinical Research Center for Digestive Diseases, Beijing, 100050, People's Republic of China.
Jie LiuDepartment of General Surgery, Beijing Friendship Hospital, Capital Medical University, State Key Laboratory of Digestive Health, National Clinical Research Center for Digestive Diseases, Beijing, 100050, People's Republic of China.
Zhonghao LiDepartment of General Surgery, Beijing Friendship Hospital, Capital Medical University, State Key Laboratory of Digestive Health, National Clinical Research Center for Digestive Diseases, Beijing, 100050, People's Republic of China.
Mingcheng ZhangDepartment of General Surgery, Beijing Friendship Hospital, Capital Medical University, State Key Laboratory of Digestive Health, National Clinical Research Center for Digestive Diseases, Beijing, 100050, People's Republic of China.
Wei GuoDepartment of General Surgery, Beijing Friendship Hospital, Capital Medical University, State Key Laboratory of Digestive Health, National Clinical Research Center for Digestive Diseases, Beijing, 100050, People's Republic of China.ORCID 0000-0002-0811-7436

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Preoperative biliary drainage is used to alleviate obstructive jaundice before pancreaticoduodenectomy in jaundiced patients, but its effect on reducing the short-term postoperative complications is still controversial. Methods: Data were collected retrospectively from patients (n = 292) with benign and malignant diseases around the ampulla who underwent pancreaticoduodenectomy in this study. Intergroup comparisons were performed using statistical methods such as t-tests and chi-square tests. The optimal preoperative total bilirubin was identified through receiver operating characteristic curve analysis. Results: A total of 292 patients (jaundiced patients:141, non-jaundice:151) were collected in this study. Compared with non-jaundice patients, the incidence of postoperative bleeding events ( Conclusion: Preoperative biliary drainage can effectively improve liver function and decrease the short-term complications after pancreaticoduodenectomy for severe jaundiced patients. Routine preoperative biliary drainage is not recommended in patients with mild jaundice. It is recommended to reduce the total bilirubin to less than 151.8μmol/L, which can effectively decrease the severe short-term postoperative complications.

Indexed as

jaundicepancreaticoduodenectomypostoperative complicationspreoperative biliary drainagetarget total bilirubin

Identifiers

PMID41229550
PMCPMC12604501

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.