ArticleJournal of thoracic disease2025
Sex differences in cardiovascular outcomes in patients with acute coronary syndrome undergoing percutaneous coronary intervention.
Article in Journal of thoracic disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Sex differences in acute coronary syndrome (ACS) presentation and outcomes have been increasingly recognized, yet data from Southeast Asian populations, particularly Thailand, remain limited. This study aimed to evaluate sex-specific differences in baseline characteristics, in-hospital mortality, and 1-year mortality among ACS patients undergoing percutaneous coronary intervention (PCI). Methods: This retrospective cohort study included 1,579 patients aged ≥18 years diagnosed with ACS who underwent PCI at King Chulalongkorn Memorial Hospital between January 2017 and October 2021. Baseline characteristics, post-procedural complications, and outcomes were compared between sexes. Primary outcomes were in-hospital and 1-year mortality. Secondary outcomes included post-procedural complications such as coronary artery complications, vascular complications, acute kidney injury, stroke, bleeding, and nosocomial infections. One-year mortality was analyzed using Cox proportional hazards models and Kaplan-Meier survival analysis. Results: Among the study population, 453 (28.7%) were women. Women were significantly older (median: 70 Conclusions: Women with ACS undergoing PCI presented with more comorbidities, atypical symptoms, and higher long-term mortality compared to men.
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