Evidence map›Paper›PMID 41229901›Full record

ArticleJournal of pain research2025

Murottal and Classical Music Effect on Pain: Clinical Trial.

M M Rudi Prihatno, Guruh Perkasa, Hermin Prihartini, Shila Suryani, Iwan D Cahyono

Abstract read
In one paragraph

Article in Journal of pain research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

M M Rudi PrihatnoDepartment of Anesthesiology and Intensive Care, Medical Faculty of Jenderal Soedirman University, Purwokerto, Central Java, Indonesia.ORCID 0000-0002-4611-0454
Guruh PerkasaDepartment of Anesthesiology and Intensive Care, Medical Faculty of Jenderal Soedirman University, Purwokerto, Central Java, Indonesia.
Hermin Prihartini *Department of Anesthesiology and Intensive Care, Medical Faculty of Jenderal Soedirman University, Purwokerto, Central Java, Indonesia.
Shila Suryani *Department of Anesthesiology and Intensive Care, Medical Faculty of Jenderal Soedirman University, Purwokerto, Central Java, Indonesia.
Iwan D Cahyono *Department of Anesthesiology and Intensive Care, Medical Faculty of Jenderal Soedirman University, Purwokerto, Central Java, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Indonesia has the highest incidence of fractures in Southeast Asia, reaching 1.3 million cases per year, with a prevalence of 5.5% in 2020, predominantly involving lower extremity fractures. Uncontrolled pain can reduce rehabilitation effectiveness and increase the risk of complications. Purpose: In some cases, long-term use of analgesics can cause detrimental side effects, necessitating the search for alternatives. Another alternative in this study, adapted to local conditions and culture, is listening to Quranic recitals accompanied by classical music. The objective of this study is to examine the effect of Quranic recitation and classical music on the Numeric Rating Scale (NRS) pain score and interleukin-6 (IL-6) levels in patients undergoing lower extremity orthopedic surgery under intrathecal anesthesia. Methods: A double-blind, randomized controlled trial (RCT) was conducted at Prof. Dr. Margono Soekarjo Hospital in Purwokerto, Central Java, Indonesia. Patients undergoing elective lower extremity orthopedic surgery who met the inclusion and exclusion criteria were randomly assigned to three groups: Group A (murottal with standard care, n = 11), Group B (classical music with standard care, n = 11), and Group C (control without music therapy with standard care, n = 11). The study compared IL-6 levels 30 minutes before and 30 minutes after surgery, as well as pain levels NRS measured 4 hours postoperatively (pre- and post-intervention) in lower extremity orthopedic surgery patients. Results: A significant difference was observed, showing that murottal reduced NRS with a p-value of <0.05 (p = 0.003), and classical music also reduced NRS with a p-value of <0.05 (p = 0.003), compared to the control group, which had a p-value of >0.05 (p = 1.000), there was no significant effect of murottal on IL-6 levels (p > 0.05, p = 0.277) or classical music on IL-6 levels (p > 0.05, p = 0.740) in patients undergoing lower extremity orthopedic surgery. Conclusion: The study results indicate the use of murottal and classical music for pain management provides better effects compared to no music intervention, there was no significant effect of murottal and classical music on IL-6 levels.

Indexed as

IL-6music therapyorthopedic surgerypostoperative painquranic recital

Identifiers

PMID41229901
PMCPMC12604499

What Socratic holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.