ArticleFrontiers in neurology2025
Concurrent functional-structural reorganization in brain networks of AVM patients: a functional and structural study.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Network Disconnection Syndrome in Unruptured Brain Arteriovenous Malformations: A Multimodal Connectome Study.CNS neuroscience & therapeutics · 2026Article
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13 authors.
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Abstract
Background: Unruptured cerebral arteriovenous malformations (AVMs) generally do not cause focal neurological deficits, prompting limited investigation into potential neurological changes associated with them. Purpose: To determine whether AVMs exhibit combined functional and structural reorganization using resting-state functional MRI (rs-fMRI) and diffusion tensor imaging (DTI). Study type: Retrospective study. Population: 44 AVM patients who underwent both rs-fMRI and DTI examinations as well as an equal number of age- and sex-matched healthy controls. Sequence: Functional alterations were assessed using amplitude of low-frequency fluctuation (ALFF) analysis and functional connectivity networks, while fiber alterations were examined through fractional anisotropy (FA) analysis and tract-weighted functional connectivity (TW-FC) analysis. Assessment: Functional alterations were evaluated by ALFF and functional connectivity networks, analyzed by neuroimaging specialists. Structural alterations were assessed through FA and TW-FC analysis, performed by experienced radiologists. Statistical tests: Independent two-sample Results: AVMs showed significant ALFF differences in 12 brain regions and altered functional connectivity networks compared to healthy controls ( Data conclusion: The study reveals significant functional and structural changes in AVM patients, particularly in the visual network (VN) and sensorimotor network (SMN). These alterations suggest compensatory mechanisms that may offset functional deficits, providing insights into AVM pathophysiology and potential strategies for optimizing treatment to mitigate functional impairments and promote recovery.
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