Evidence map›Paper›PMID 41231304›Full record

ArticleJournal of medical systems2025

RAG-Enhanced Open SLMs for Hypertension Management Chatbots.

Gianluca Aguzzi, Matteo Magnini, Aqila Farahmand, Stefano Ferretti, Martino Francesco Pengo, Sara Montagna

Abstract read
In one paragraph

Article in Journal of medical systems, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gianluca AguzziDepartment of Computer Science and Engineering, University of Bologna, Cesena, Italy.
Matteo MagniniDepartment of Computer Science and Engineering, University of Bologna, Cesena, Italy.
Aqila FarahmandDepartment of Pure and Applied Sciences, University of Urbino, Urbino, Italy.
Stefano FerrettiDepartment of Computer Science and Engineering, University of Bologna, Cesena, Italy.
Martino Francesco PengoSchool of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.
Sara MontagnaDepartment of Pure and Applied Sciences, University of Urbino, Urbino, Italy. sara.montagna@uniurb.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic disease management requires continuous monitoring, lifestyle modification and therapy adherence, thus requiring constant support from healthcare professionals. Chatbots have proven to be a promising approach for engaging patients in managing their health condition at home and for offering continuous assistance by being readily available to answer questions. While large language models offer an impressive solution for chatbot implementation, third-party systems raise privacy concerns, and computational requirements limit small-scale deployment. We address these challenges by developing a chatbot for hypertensive patients based on open-source small language models (SLMs), specifically designed for running on personal resource-constrained devices and for providing assistance in QA tasks. In order to guarantee comparable conversational performances with respect to larger language models, we exploited retrieval-augmented generation (RAG) with a local knowledge base. This ensures data privacy by deploying models locally while achieving competitive accuracy and maintaining low computational costs suitable for end-user devices. We experimented with eight SLMs, two prompt configurations, and different RAG strategies - both in the embedding and retrieval components - to identify the most effective solution. The evaluation of our solution grounds on both reference metrics and expert evaluation. Our findings suggest that RAG-enhanced SLMs can improve response clarity and content accuracy. However, our results also indicate that newer SLMs like Qwen3 demonstrate strong performance even without RAG, suggesting a potential shift in the necessity for complex retrieval mechanisms with rapidly evolving model architectures.

Indexed as

HypertensionGenerative Artificial IntelligenceHumansTelemedicineChronic disease self-managementHypertensionLarge language modelsRetrieval-augmented generation

Identifiers

PMID41231304
PMCPMC12615560

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.