Evidence map›Paper›PMID 41232773›Full record

Trial reportThe Journal of nutrition2026

Fat Amount Rather Than Fatty Acid Composition Influences Postprandial Hunger, Satiety and Attention in Men and Women with a Risk Phenotype for Cardiometabolic Diseases: A Randomized Crossover Trial.

Christina Diekmann, Tim B Schiemann, Hannah F Kienēs, Carolin Wiechmann, Christina Kopp, Birgit Stoffel-Wagner, Martin Coenen, Robert Németh, Michael Wagner, Sarah Egert

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The Journal of nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05208346 (Acute Effects of Canola Oil Compared With Coconut Oil on Postprandial Metabolism in Women and Men With Increased Risk for Cardiometabolic Diseases), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05208346 nacompletednot on this map

Acute Effects of Canola Oil Compared With Coconut Oil on Postprandial Metabolism in Women and Men With Increased Risk for Cardiometabolic Diseases

TypeinterventionalSponsorUniversity of BonnRan2022 to 2022Enrolled30ConditionsCardiovascular Diseases, Metabolic SyndromeArmsMixed meals
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Christina DiekmannInstitute of Nutritional and Food Sciences, Nutritional Physiology, University of Bonn, Bonn, Germany.
Tim B SchiemannInstitute of Nutritional and Food Sciences, Nutritional Physiology, University of Bonn, Bonn, Germany.
Hannah F KienēsInstitute of Nutritional and Food Sciences, Nutritional Physiology, University of Bonn, Bonn, Germany.
Carolin WiechmannInstitute of Nutritional and Food Sciences, Nutritional Physiology, University of Bonn, Bonn, Germany.
Christina KoppInstitute of Nutritional and Food Sciences, Nutritional Physiology, University of Bonn, Bonn, Germany.
Birgit Stoffel-WagnerInstitute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany.
Martin CoenenInstitute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany.
Robert NémethInstitute of Medical Biometry, Informatics and Epidemiology, University Hospital Bonn, Bonn, Germany.
Michael WagnerDepartment of Old Age Psychiatry and Cognitive Disorders, University Hospital Bonn, Bonn, Germany; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
Sarah EgertInstitute of Nutritional and Food Sciences, Nutritional Physiology, University of Bonn, Bonn, Germany. Electronic address: s.egert@uni-bonn.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHunger and satiety are influenced by both the amount and composition of dietary fat.

objectivesThis exploratory analysis examined the effects of meals enriched with different amounts of either canola oil (rich in unsaturated fatty acids) or coconut oil (rich in saturated fatty acids) on postprandial changes in subjective hunger and satiety ratings, related hormones, attention, and memory.

methodsTwenty-nine participants with an increased cardiometabolic disease risk (e.g., body mass index, 30.2 ± 2.6 kg/m

resultsLower serum ghrelin levels were observed after canola oil meals [canola compared with coconut: -27,700 (confidence interval: -40,700, -14,700) min × pg/mL] with no effect of fat amount on incremental area under the curve data [HFM compared with LFM: -9500 (-22,500, 3500) min × pg/mL]. Serum PYY concentrations were higher after HFMs [HFM compared with LFM: 8600 (2100, 15,200) min × pg/mL]. LFMs resulted in lower subjective hunger ratings compared with HFMs [HFM compared with LFM: 250 (71, 430) min × score-value].

conclusionsOur data indicate that predominantly the amount of dietary fat, rather than its type, affects hunger and satiety. At the hormonal level, canola oil suppressed postprandial hunger to a greater extent than coconut oil. This trial was registered at ClinicalTrials.gov (https://clinicaltrials.gov/) as NCT05208346.

Indexed as

AttentionCardiovascular DiseasesDietary FatsFatty AcidsHungerPostprandial PeriodSatiationAdultCoconut OilCross-Over StudiesFemaleGhrelinHumansMaleMiddle AgedRapeseed OilCoconut OilDietary FatsFatty AcidsGhrelinRapeseed Oilattentioncanola oilcoconut oilpostprandial metabolismsatiety

Identifiers

PMID41232773
PMCPMC12881678

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.