Evidence map›Paper›PMID 41233865›Full record

ArticleInternational journal for equity in health2025

Sexual-orientation disparities in whole person health: age- and gender-stratified analysis of patients in a safety-net system.

Dhruv Khurana, Maryah Garner, Brittany Bass, Bijan Sasininia, Geoffrey Leung, Anthony Firek

Abstract read
In one paragraph

Article in International journal for equity in health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dhruv KhuranaDepartment of Psychiatry and Biobehavioral Sciences, UCLA David Geffen School of Medicine, Los Angeles, CA, USA. dhruvkhurana@ucla.edu.
Maryah GarnerComparative Effectiveness and Clinical Outcomes Research Center, Riverside University Health System-Medical Center, Riverside County, Moreno Valley, CA, USA.
Brittany BassDepartment of Psychiatry and Biobehavioral Sciences, UCLA David Geffen School of Medicine, Los Angeles, CA, USA.
Bijan SasininiaComparative Effectiveness and Clinical Outcomes Research Center, Riverside University Health System-Medical Center, Riverside County, Moreno Valley, CA, USA.
Geoffrey LeungDepartment of Public Health, Riverside County, Moreno Valley, CA, USA.
Anthony FirekComparative Effectiveness and Clinical Outcomes Research Center, Riverside University Health System-Medical Center, Riverside County, Moreno Valley, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDespite advancements in LGB+ rights, LGB+ individuals continue to face significant healthcare disparities, particularly in areas such as homelessness, mental health, substance use, health service access, and victimization. Addressing these disparities is essential to improving the quality of life and health outcomes for this population. This study examines the comprehensive health needs of LGB+ individuals using a Whole Person Health (WPH) approach, which includes Social Determinants of Health (SDOH) as well as other critical aspects of well-being, through EHR-based Sexual Orientation and Gender Identity (SOGI) data within a safety-net health system.

methodsThis cross-sectional study utilizes the EHR-embedded Whole Person Health Score (WPHS) and SOGI tools to assess the SDOH needs of 34,423 heterosexual, 1,213 LGB+, and 384 Other patients. Transgender and gender-fluid patients were excluded for a separate study. The WPHS incorporates self-reported factors across six domains, providing letter grades converted to numerical values and color-coded intervention levels. Data from August 2020 to July 2023 were analyzed.

resultsRelative to heterosexual peers, LGB+ adults showed consistently higher emotional-health burdens - depression (18-25: +24.1 pp, 95% CI 18.7-29.6; 26-45: +17.0 pp, 13.2-20.9; 46+: +7.2 pp, 1.0-13.3) and anxiety (18-25: +22.9 pp, 18.0-27.8; 26-45: +16.6 pp, 13.0-20.3; 46+: +10.1 pp, 4.1-16.2), with similar elevations by gender (e.g. cis female LGB+ depression +18.0 pp, 14.3-21.6). Social adversity was higher across ages, inadequate finances (18-25: +21.5 pp, 16.0-27.1; 26-45: +13.3 pp, 9.6-17.0), food access (+16.0, +10.8, +6.8 pp for 18-25, 26-45, 46+, respectively), and transportation (+11.6 and +10.5 pp for 18-25 and 26-45). Utilization rose for office visits (26-45: +7.4 pp, 3.5-11.4) and prescription use (18-25: +13.5 pp, 7.8-19.2; 26-45: +12.5 pp, 8.7-16.3; 46+: +5.7 pp, 1.9-9.6). Notably, LGB+ adults were more educated (lower "lack of higher education": 26-45 -11.5 pp, -15.4 to -7.5; 46 + -24.3 pp, -30.4 to -18.1; male LGB+ -22.1 pp, -26.4 to -17.7). Physical-condition differences were mixed (e.g. male LGB+ fewer chronic conditions -10.1 pp, -14.4 to -5.7; fewer functional limitations -13.1 pp, -16.7 to -9.4).

conclusionThe WPHS tool highlighted substantial disparities in mental health, substance use, and economic challenges among LGB+ individuals, emphasizing the importance of tailored interventions. Our findings advocate for the routine collection of SOGI data and integrating social and non-medical needs in patient care to effectively address these disparities.

Indexed as

Healthcare DisparitiesHealth Status DisparitiesSafety-net ProvidersSexual and Gender MinoritiesSexual BehaviorAdolescentAdultAgedAge FactorsCross-Sectional StudiesFemaleHumansMaleMental HealthMiddle AgedSocial Determinants of HealthElectronic health recordsHealth disparitiesLesbian, gay, bisexualLGBTQPatient-reported outcomesSafety-net health systemSexual and gender minoritiesSexual orientationSOGIWhole person health score

Identifiers

PMID41233865
PMCPMC12617001

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.