Evidence map›Paper›PMID 41234125›Full record

ArticleJournal of the International Neuropsychological Society : JINS2025

Longitudinal neurocognitive outcomes in children with mild traumatic brain injury: An ABCD cohort analysis.

Nicola L de Souza, Wenjing Meng, Florin Vaida, Joanna Jacobus, Elisabeth A Wilde, Emily L Dennis, Erin D Bigler, Xia Yang, Michael Cheng, Emily A Troyer and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the International Neuropsychological Society : JINS, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Nicola L de SouzaTraumatic Brain Injury and Concussion Center, Department of Neurology, University of Utah School of Medicinehttps://ror.org/03r0ha626, Salt Lake City, UT, USA.ORCID https://orcid.org/0000-0003-2166-428X
Wenjing MengDivision of Biostatistics and Bioinformatics, School of Public Health, University of California San Diego, La Jolla, CA, USA.
Florin VaidaDivision of Biostatistics and Bioinformatics, School of Public Health, University of California San Diego, La Jolla, CA, USA.
Joanna JacobusDepartment of Psychiatry, University of California San Diego, La Jolla, CA, USA.
Elisabeth A WildeTraumatic Brain Injury and Concussion Center, Department of Neurology, University of Utah School of Medicinehttps://ror.org/03r0ha626, Salt Lake City, UT, USA.
Emily L DennisTraumatic Brain Injury and Concussion Center, Department of Neurology, University of Utah School of Medicinehttps://ror.org/03r0ha626, Salt Lake City, UT, USA.
Erin D BiglerTraumatic Brain Injury and Concussion Center, Department of Neurology, University of Utah School of Medicinehttps://ror.org/03r0ha626, Salt Lake City, UT, USA.
Xia YangDepartment of Integrative Biology and Physiology, University of California, Los Angeles, CA, USA.
Michael ChengDepartment of Integrative Biology and Physiology, University of California, Los Angeles, CA, USA.
Emily A TroyerDepartment of Psychiatry, University of California San Diego, La Jolla, CA, USA.
Tracy AbildskovTraumatic Brain Injury and Concussion Center, Department of Neurology, University of Utah School of Medicinehttps://ror.org/03r0ha626, Salt Lake City, UT, USA.
John R HesselinkDepartment of Radiology, University of California San Diego, La Jolla, CA, USA.
Jeffrey E MaxDepartment of Psychiatry, University of California San Diego, La Jolla, CA, USA.ORCID https://orcid.org/0000-0002-6566-1585

Funding

ABCD-USA Consortium: Research ProjectU01DA041089 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Joanna Jacobus, Susan F. Tapert · 2015 to 2026
$31.7M
Cannabis and Nicotine Co-Use Influences on Protracted Development of Neural Structure and FunctionR01DA054106 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Joanna Jacobus · 2021 to 2026
$3.2M
Pediatric Mild Traumatic Brain Injury and the ABCD Study: A Prospective Behavioral, Psychiatric, Neurocognitive, Imaging, and Genetic InvestigationR01HD105338 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JEFFREY Edwin MAX · 2022 to 2026
$2.3M
NICHD NIH HHS R01 HD105338NIDA NIH HHS R01 DA054106NIDA NIH HHS U01 DA041089
6 · The paper itself

Abstract

objectivesMost children recover from mild traumatic brain injury (mTBI), but some experience persistent neurocognitive effects. Understanding is limited due to methodological differences and a lack of pre-injury data. The study aimed to assess changes in neurocognitive outcomes in children following mTBI compared to orthopedic injury (OI) and non-injured (NI) controls, while accounting for pre-injury functioning.

methodData were drawn from the Adolescent Brain and Cognitive Development (ABCD) study, a prospective longitudinal cohort. The sample included children with mTBI between the 1-year and 2-year follow-ups (

resultsAt baseline prior to injury, the mTBI group demonstrated better performance on picture vocabulary and crystallized composite scores than the OI group. At post-injury, after adjusting for pre-injury baseline differences, children who sustained an mTBI were no different in any measure of neurocognitive outcomes compared to OI and NI controls.

conclusionsThe findings highlight the importance of accounting for pre-injury differences when evaluating neurocognitive outcomes following pediatric mTBI. Neurocognitive differences within a year post-injury may be more related to pre-existing individual factors rather than the injury itself, underscoring the need for a comprehensive approach in studying pediatric mTBI.

Indexed as

cognitionconcussioncontrol group comparisonlongitudinal analysisPediatric traumatic brain injurypre-injury functioning

Identifiers

PMID41234125
PMCPMC12626387

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.