ReviewPain reports2025
Roles of noncoding RNAs in neuropathic pain.
Review in Pain reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- New insight into RNA biomarkers in neuropathic pain: a clinician-neuroscientist roadmap to translational testing and treatment monitoring a clinical review.Frontiers in pain research (Lausanne, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neuropathic pain is caused by a lesion or disease of the somatosensory (peripheral or central) nervous system. Most patients are associated with persistent or intermittent spontaneous pain. Intercellular interactions and molecular signaling underlie injury sensitization. These include abnormal expression of ion channels, epigenetic modulation, etc. Noncoding RNAs (ncRNAs) mainly include microRNA (miRNA), long noncoding RNA, and circular RNA. Recent studies have increasingly demonstrated the involvement of ncRNAs in the development and progression of neuropathic pain. This involves multiple regulatory mechanisms, including direct targeting of ncRNAs to downstream target genes, internal "sponge" regulation of ncRNAs, and a complex regulatory network between multiple ncRNAs and target genes. Within this comprehensive paper, a thorough analysis is conducted on the intricate biological functions of 3 distinct ncRNAs in relation to chronic neuropathic pain. Furthermore, the study investigates the utilization of animal models to better comprehend this condition and explores the promising possibilities of ncRNAs for diagnosing and treating neuropathic pain. The ultimate objective of this review is to offer fresh perspectives on the management and prevention of neuropathic pain.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.