ArticleTurkish journal of medical sciences2025
Assessment of alterations in regional homogeneity and amplitude of low-frequency fluctuations in children with dyslexia.
Article in Turkish journal of medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background/aim: Exploratory methods in neuroimaging are gaining increasing attention for revealing functional connectivity structures across the entire brain. This study aims to contribute to the understanding of the functional mechanisms underlying dyslexia, along with the effects of specialized education for dyslexia treatment, by utilizing measures such as regional homogeneity (ReHo), amplitude of low-frequency fluctuations (ALFF), and fractional ALFF (fALFF). Materials and methods: Resting-state functional magnetic resonance imaging data were collected from three groups of Turkish-speaking children aged 7-12: diagnosed with dyslexia for the first time (Dys, n = 19), children with dyslexia who received specialized education (EDys, n = 20), and healthy controls (HC, n = 27). In the study, brain activation in individuals with dyslexia was examined through resting-state analyses employing the ReHo, ALFF, and fALFF methods. Results: Significant reductions in ReHo and ALFF values were observed in brain regions associated with phonological processing and visuomotor integration in children with dyslexia. These findings indicate altered neural synchronization related to cognitive deficits in reading and language processing. Compared to HC, children with Dys showed significantly reduced ReHo and ALFF values in the left precuneus and middle frontal gyrus, while those EDys exhibited compensatory increases in calcarine and lingual gyri. Conclusion: This study provides valuable insights into the resting-state neural connectivity of individuals with dyslexia, highlighting the impact of specialized educational programs in treating dyslexia. Our findings contribute to understanding the altered connectivity foundations of dyslexia compared to healthy children and support the development of educational interventions within this framework.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.