Evidence map›Paper›PMID 41234506›Full record

ArticleJournal of inflammation research2025

Prognostic Value of Systemic Inflammation Scores in Patients with Acute Coronary Syndrome Who Underwent Percutaneous Coronary Intervention: A Prospective Cohort Study.

Xinchen Wang, Linlin Wang, Yuewen Qi, Yan Liu, Ying Zhang, Ge Song, Qiyu Sun, Chen Wei, Jingyi Liu, Fei Shi and 1 more

Abstract read
In one paragraph

Article in Journal of inflammation research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xinchen Wang *Department of Cardiology, The Affiliated Hospital of Chengde Medical University, Chengde, People's Republic of China.ORCID 0000-0002-6169-665X
Linlin Wang *Department of Cardiology, The Affiliated Hospital of Chengde Medical University, Chengde, People's Republic of China.ORCID 0009-0005-6005-7900
Yuewen QiHebei Key Laboratory of Panvascular Diseases, Chengde, People's Republic of China.ORCID 0000-0003-4683-9402
Yan LiuDepartment of Cardiology, The Affiliated Hospital of Chengde Medical University, Chengde, People's Republic of China.
Ying ZhangDepartment of Cardiology, The Affiliated Hospital of Chengde Medical University, Chengde, People's Republic of China.
Ge SongDepartment of Cardiology, The Affiliated Hospital of Chengde Medical University, Chengde, People's Republic of China.ORCID 0009-0006-5116-7208
Qiyu SunCentral Laboratory, The Affiliated Hospital of Chengde Medical University, Chengde, People's Republic of China.ORCID 0000-0002-2526-7823
Chen WeiDepartment of Cardiology, The Affiliated Hospital of Chengde Medical University, Chengde, People's Republic of China.ORCID 0000-0001-7615-4215
Jingyi LiuDepartment of Cardiology, The Affiliated Hospital of Chengde Medical University, Chengde, People's Republic of China.
Fei ShiDepartment of Cardiology, The Affiliated Hospital of Chengde Medical University, Chengde, People's Republic of China.ORCID 0000-0002-8779-3263
Lixian SunDepartment of Cardiology, The Affiliated Hospital of Chengde Medical University, Chengde, People's Republic of China.ORCID 0000-0001-9814-0965

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Acute coronary syndrome (ACS) is closely associated with inflammation status. The systemic inflammation score (SIS), which is calculated using the serum albumin level and lymphocyte-to-monocyte ratio (LMR), has emerged as a valuable biomarker for predicting the clinical outcomes of several diseases. Nonetheless, the value of SIS in predicting the long-term prognostic risk in patients with ACS undergoing percutaneous coronary intervention (PCI) remains unknown. We aimed to explore the associations of SIS with major adverse cardiovascular events (MACEs), all-cause mortality, and cardiovascular death. Methods: This prospective cohort study consecutively enrolled 1582 patients with ACS who underwent PCI at the Department of Cardiology in the Affiliated Hospital of Chengde Medical University (Chengde, China) between January 2016 and December 2018. The primary endpoint was MACEs, including all-cause mortality, rehospitalization for heart failure, revascularization, recurrence of acute myocardial infarction, and restenosis/intrastent thrombosis. Results: The Kaplan-Meier survival analysis revealed that a high SIS was correlated with MACEs and all-cause mortality and that increasing SIS was independently associated with the risks of MACEs and all-cause mortality by Cox regression. Landmark analysis provided evidence for the time window of predictive ability, which could guide clinical applications. A clear correlation between the increasing tendency of hazard ratio in patients with ACS undergoing PCI and the risks of MACEs or all-cause mortality was noted ( Conclusion: The SIS exhibited a strong correlation with the risks of MACEs and all-cause mortality. Notably, the SIS was particularly effective in predicting the risk of cardiac death and likelihood of rehospitalization.

Indexed as

acute coronary syndromepercutaneous coronary interventionprognosissystemic inflammation score

Identifiers

PMID41234506
PMCPMC12607720

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.