ArticleFrontiers in immunology2025
Electrode impedance dynamics in sequential cochlear implant users: insights into cochlear immunity.
Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Interaural correlation of acoustic hearing preservation following sequential cochlear implantation.Frontiers in neurology · 2025Article
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5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Introduction: Cochlear implant outcomes can be limited due to immunologically mediated intracochlear foreign body responses, resulting in new bone growth and fibrosis. Minimal consideration has been given to the possible role of immunological memory in modulating this response in sequentially implanted patients. We hypothesize the first implant primes the contralateral ear to respond more robustly to sequential implantation, leading to earlier increases in electrode impedance. Methods: This is a retrospective cohort analysis of clinical impedance measurements from 79 subjects with sequential bilateral implants. Raw impedance and changes in impedance were analyzed over time according to implant sequence. Results: Paired Discussion: More rapid increases and greater electrode impedances are consistent with a more robust immune response in the second implanted ear. Additional investigation into the effects of implant timing, electrode array type, perioperative corticosteroids, and complex impedances may further elucidate these relationships and their implications for the cochlear immune response.
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