Evidence map›Paper›PMID 41235310›Full record

ArticleFrontiers in nutrition2025

Relationship between serum mineral levels in the second and third trimester of pregnancy and the risk of gestational diabetes mellitus: a retrospective cohort study.

Yuxin Hao, Na Wang, Sumiao Hong, Yongyi Liu, Guankai Lin, Xiaoyang Xu, You Zhou, Xiaoting Wen, Baochang Sun, Hexing Wang and 4 more

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Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

14 authors.

Yuxin Hao *Key Lab of Health Technology Assessment of Ministry of Health, School of Public Health, Fudan University, Shanghai, China.
Na Wang *Department of Obstetrics, The People's Hospital of Pingyang, Wenzhou, Zhejiang, China.
Sumiao HongDepartment of Obstetrics, The People's Hospital of Pingyang, Wenzhou, Zhejiang, China.
Yongyi LiuJoseph L. Mailman School of Public Health, Columbia University, New York, NY, United States.
Guankai LinWenzhou Center for Disease Control and Prevention, Wenzhou, Zhejiang, China.
Xiaoyang XuDepartment of Obstetrics, The People's Hospital of Pingyang, Wenzhou, Zhejiang, China.
You ZhouDepartment of Obstetrics, The People's Hospital of Pingyang, Wenzhou, Zhejiang, China.
Xiaoting WenDepartment of Obstetrics, The People's Hospital of Pingyang, Wenzhou, Zhejiang, China.
Baochang SunWenzhou Center for Disease Control and Prevention, Wenzhou, Zhejiang, China.
Hexing WangKey Lab of Health Technology Assessment of Ministry of Health, School of Public Health, Fudan University, Shanghai, China.
Min HuangDepartment of Obstetrics, The People's Hospital of Pingyang, Wenzhou, Zhejiang, China.
Jiwei WangKey Lab of Health Technology Assessment of Ministry of Health, School of Public Health, Fudan University, Shanghai, China.
Yue ChenSchool of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.
Qingwu JiangKey Lab of Health Technology Assessment of Ministry of Health, School of Public Health, Fudan University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Gestational diabetes mellitus (GDM) poses significant health risks for both the mother and fetus, and it also increases the mother's risk of developing type 2 diabetes later in life. Mineral elements may play a crucial role in the development of GDM by influencing insulin metabolism. However, comprehensive studies on serum mineral levels during pregnancy remain limited. This study aims to evaluate the relationship between serum mineral levels in pregnant women during the second and third trimesters and the risk of developing GDM. Methods: This retrospective cohort study included 17,224 singleton pregnancies delivered between 2016 and 2022 at a tertiary hospital in China. Maternal demographic data and serum mineral concentration information from the mid and late stages of pregnancy were collected through the hospital information system. Analyses were conducted using restricted cubic spline models and multivariate logistic regression models. Results: The prevalence of GDM in this study was 15.07%. Chloride [ Discussion: The study indicates that specific serum mineral levels in pregnant women are closely associated with the risk of gestational diabetes mellitus. A deeper understanding of the mechanisms and interactions of these minerals could aid in developing effective prevention and treatment strategies, thereby reducing the incidence of GDM and improving pregnancy outcomes.

Indexed as

gestational agegestational diabetes mellitusmicronutrientsmineralretrospective study

Identifiers

PMID41235310
PMCPMC12605074

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.