SynthesisFrontiers in nutrition2025
Impact of digital health technology-based nutritional interventions on the nutritional status of hemodialysis patients: a systematic review and meta-analysis.
Synthesis in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Global Research on Hemodialysis Nutrition and Patient-Centered Priorities: A Bibliometric Analysis (2006-2025).Healthcare (Basel, Switzerland) · 2025Article
- Digital health technology empowering China's community full life cycle health management.Digital healthReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Chronic kidney disease (CKD) imposes a growing global burden, with hemodialysis (HD) patients facing high malnutrition rates (28% ~ 54%). Nutritional management is critical but challenging due to strict dietary restrictions and limited healthcare monitoring. Digital health technologies (DHTs) offer dynamic, personalized interventions, yet their efficacy remains inconsistent. This systematic review and meta-analysis aims to assess the effects of DHT-based nutritional interventions on the nutritional status of hemodialysis patients. Methods: We systematically searched PubMed, Embase, Cochrane Library, Web of Science, CINAHL, Scopus, CNKI, CBM, WanFang, and VIP databases from their inception to 21 March 2025, to investigate the impact of DHTs-based nutritional interventions on the nutritional status of hemodialysis patients. Outcomes included biochemical parameters, anthropometric measures, and Modified Quantitative Subjective Global Assessment (MQSGA). Risk-of-bias assessment used Cochrane criteria, and meta-analyses employed RevMan 5.4 with random/fixed-effects models. Results: A total of 23 literatures were included, involving 6 countries and 2,762 hemodialysis patients. DHT interventions improved the following 13 outcome measures: MQSGA, hemoglobin, albumin, prealbumin, phosphorus, potassium, BMI, mid-arm muscle circumference, triceps skinfold thickness, relative increase in body weight (%), weight gain, blood urea nitrogen, and serum creatinine. However, it had no significant effect on transferrin and calcium. The intervention forms are mainly applications and mobile platforms. Conclusion: Overall, DHT-based nutritional interventions effectively enhance multiple nutritional indicators in HD patients. However, variability in study quality, intervention formats, and regional disparities limits generalizability. Future research should prioritize high-quality, multicenter RCTs to optimize intervention protocols and explore emerging technologies. Systematic review registration: Identifier PROSPERO: CRD420251023133.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.