Evidence map›Paper›PMID 41235697›Full record

ReviewMolecular oncology2026

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology.

Marius Ilié, Umberto Malapelle, Catherine Alix-Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet-Fabre, Olivier Bordone, Simon Heeke and 4 more

Abstract readReview
In one paragraph

Review in Molecular oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Liquid biopsy in solid tumours: expert opinion paper of the European society of pathology.Virchows Archiv : an international journal of pathology · 2026
    Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Marius IliéLaboratory of Clinical and Experimental Pathology, Hospital-Integrated Biobank (BB-0033-00025), IHU RespirERA, FHU OncoAge, University Hospital Centre Nice, University Côte d'Azur, France.ORCID 0000-0002-2014-1236
Umberto MalapelleDepartment of Public Health, University Federico II of Naples, Italy.
Catherine Alix-PanabièresLaboratory of Rare Human Circulating Cells (LCCRH) and Liquid Biopsy, University Medical Centre of Montpellier, France.ORCID 0000-0002-6401-2903
Claus Lindbjerg AndersenDepartment of Molecular Medicine, Aarhus University Hospital, Denmark.ORCID 0000-0002-7406-2103
Sandra ChlebowskiUniversity Côte d'Azur, Initiative of Excellence, Nice, France.
Vivien LakeCenter for Active Learning and MSc International Office, IDEX Université Côte d'Azur, Nice, France.
Caroline LacouxLaboratory of Clinical and Experimental Pathology, Hospital-Integrated Biobank (BB-0033-00025), IHU RespirERA, FHU OncoAge, University Hospital Centre Nice, University Côte d'Azur, France.
Virginie Lespinet-FabreLaboratory of Clinical and Experimental Pathology, Hospital-Integrated Biobank (BB-0033-00025), IHU RespirERA, FHU OncoAge, University Hospital Centre Nice, University Côte d'Azur, France.
Olivier BordoneLaboratory of Clinical and Experimental Pathology, Hospital-Integrated Biobank (BB-0033-00025), IHU RespirERA, FHU OncoAge, University Hospital Centre Nice, University Côte d'Azur, France.
Simon HeekeDepartment of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Christophe BontouxDepartment of Pathology, Cancer University Institute of Toulouse-Oncopole, France.
Ellen HeitzerInstitute of Human Genetics, Diagnostic and Research Center for Molecular BioMedicine, Medical University of Graz, Austria.ORCID 0000-0002-8815-7859
Klaus PantelEuropean Liquid Biopsy Society (ELBS), Hamburg, Germany.
Paul HofmanLaboratory of Clinical and Experimental Pathology, Hospital-Integrated Biobank (BB-0033-00025), IHU RespirERA, FHU OncoAge, University Hospital Centre Nice, University Côte d'Azur, France.

Funding

Agence Nationale de la Recherche ANR-23-IAHU-007
6 · The paper itself

Abstract

Liquid biopsy has transformed molecular oncology by enabling noninvasive, real-time monitoring of cancer progression, treatment responses, and detection of minimal residual disease. Despite technological advances, educational gaps, regarding standardized, comprehensive training for molecular pathologists, remain. To address these, a new educational program, the European Masters in Molecular Pathology (EMMP) developed a dedicated educational module aimed at providing pathologists with specialized competencies in liquid biopsy. In this perspective, we discuss how embedding liquid biopsy training within the integrative pathology framework, linking molecular diagnostics, histopathological findings, and clinical context, enhances diagnostic accuracy and therapeutic decision-making in the clinic. Furthermore, we emphasize the importance of decentralizing liquid biopsy expertise to local pathology units, reducing dependency on external commercial platforms, ensuring data sovereignty, and enabling rapid, cost-effective diagnostics. Finally, integrating health policy and ethical considerations within liquid biopsy education prepares future molecular pathologists to engage meaningfully in shaping policy frameworks that support equitable and sustainable clinical implementation of precision oncology. In summary, we propose the EMMP module as a comprehensive educational strategy for training molecular pathologists in the latest liquid biopsy technologies and advancements.

Indexed as

Medical OncologyNeoplasmsPathologistsPathology, MolecularPrecision MedicineHumansLiquid BiopsycfDNACTCctDNAeducationEMMPliquid biopsymolecular pathology

Identifiers

PMID41235697
PMCPMC13060639

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.