ReviewOrthopadie (Heidelberg, Germany)2026
[Whole-body cryotherapy for low back pain].
Review in Orthopadie (Heidelberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
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0 citing papers in PubMed.
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWhole-body cryotherapy (WBC) is a cold treatment with temperatures ranging from -60 °C to -180 °C and was first used in 1980 by Yamauchi in Japan to treat rheumatoid arthritis. Outside Japan, this therapeutic method was first used in Germany in 1984. An air temperature of -120 to -110 °C cools the skin surface to as low as 5 °C, but does not change core body temperature. MODE OF FUNCTION: The cold stimulates the Aδ afferents thermally and inhibits the transmission of pain signals via the C-nerve fiber system from the spinal cord to the brain (information from the thermoreceptors and nociceptors has the same afferent pathways in the spinal cord-"conduction competition"). Furthermore, the Aδ afferent influx in the central nervous system (cortex, limbic system, thalamus) influences pain assessment and pain perception with corresponding efferent effects. In addition, WBC causes biochemical, hormonal, and immunomodulatory changes as well as accompanying muscle relaxation. APPLICATION SPECTRUM: WBC is increasingly being used in the treatment of back pain, fibromyalgia syndrome, and depression. Back pain, fibromyalgia syndrome, and depression often occur together. WBC is a component of multimodal treatment for back pain, especially when fibromyalgia syndrome or depression is also present.
Indexed as
Identifiers
41236549What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.