Evidence map›Paper›PMID 41236610›Full record

SynthesisCurrent cardiology reports2025

The Effects of Energy Drinks on the Cardiovascular System: A Systematic Review.

Joseph Mandato, Rei Kola, Troy Tyson, Luke Laffin, Robert Bales

Abstract readSystematic Review
In one paragraph

Synthesis in Current cardiology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. [Performance-related substance use in everyday life and work].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2026
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joseph MandatoCleveland Clinic Akron General Family Medicine Residency, Akron, OH, 44307, USA. tt52152@ohio.edu.
Rei KolaMetroHealth Family Medicine Residency, Cleveland, OH, 44195, USA.
Troy TysonOhio University Heritage College of Osteopathic Medicine-Cleveland, Cleveland, OH, 44195, USA.
Luke LaffinCleveland Clinic South Pointe Hospital Medicine, Warrensville, OH, 44122, USA.
Robert BalesCleveland Clinic South Pointe Hospital, 20000 Harvard Ave, Warrensville Heights, OH, 44122, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionEnergy drinks are widely marketed to enhance alertness and performance, making them a rapidly growing industry valued at $73.99 billion. These beverages typically contain caffeine and other stimulants, but their consumption has raised concerns about potential cardiovascular risks, including arrhythmias, tachycardia, and hypertension, particularly among young adults. While moderate caffeine intake may offer health benefits, excessive consumption of energy drinks has been linked to increased cardiovascular risks. This systematic review aims to explore the cardiovascular effects of energy drink consumption, identify knowledge gaps, and guide clinicians in making recommendations.

methodsA comprehensive literature search was conducted across multiple databases, including CENTRAL, CINAHL, MEDLINE, PubMed, and others. Studies were screened for those involving energy drink consumption and cardiovascular outcomes such as heart rate, blood pressure, and ECG changes. After screening abstracts, full-text articles were reviewed based on inclusion criteria: participants aged 13+, energy drink consumption, and relevant cardiovascular endpoints.

resultsA total of 1,444 references were screened, resulting in 37 studies with 1,597 participants (mean age 22.6). Red Bull and Monster were the most studied brands. Results showed significant cardiovascular effects, including increased heart rate (60.9%), systolic blood pressure (53.8%), diastolic blood pressure (61.5%), and QTc interval prolongation (63.2%). Other ECG changes, such as PR interval and T-wave alterations, were observed in 57.9% of studies.

conclusionThis review highlights the cardiovascular risks of energy drinks, including increased heart rate, blood pressure, and QTc prolongation. Future research should focus on at-risk groups and long-term effects.

Indexed as

CaffeineCardiovascular DiseasesCardiovascular SystemEnergy DrinksBlood PressureCentral Nervous System StimulantsHeart RateHumansCaffeineCentral Nervous System StimulantsBlood pressureCaffeineECGHeart rate (Variability)

Identifiers

PMID41236610
PMCPMC12618331

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.