Evidence map›Paper›PMID 41236751›Full record

ArticleJournal of the American Chemical Society2025

Protein and Solvent Reorganization Drives Radical Pair Stability in Avian Cryptochrome 4a.

Jiate Luo, Jonathan Hungerland, Ilia A Solov'yov, Joseph E Subotnik, Sharon Hammes-Schiffer

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jiate LuoDepartment of Chemistry, Princeton University, Princeton, New Jersey 08544, United States.
Jonathan HungerlandInstitut für Physik, Carl von Ossietzky-Universität Oldenburg, Carl-von-Ossietzky Str. 9-11, Oldenburg D-26129, Germany.
Ilia A Solov'yovInstitut für Physik, Carl von Ossietzky-Universität Oldenburg, Carl-von-Ossietzky Str. 9-11, Oldenburg D-26129, Germany.ORCID 0000-0002-8626-145X
Joseph E SubotnikDepartment of Chemistry, Princeton University, Princeton, New Jersey 08544, United States.ORCID 0000-0003-2170-2020
Sharon Hammes-SchifferDepartment of Chemistry, Princeton University, Princeton, New Jersey 08544, United States.ORCID 0000-0002-3782-6995

Funding

Coupled Protons and Electrons in Biological SystemsR35GM139449 · NIGMS · YALE UNIVERSITY · PI HAMMES-SCHIFFER, SHARON · 2021 to 2025
$2.1M
NIGMS NIH HHS R35 GM139449
6 · The paper itself

Abstract

Within the photoreceptor cells of avian retinas, cryptochrome-4a (Cry4a) has been proposed as a magnetic compass sensor in migratory songbirds. Recent photochemistry studies have demonstrated that Cry4a from the night-migratory European robin (

Indexed as

CryptochromesSolventsAnimalsFree RadicalsMolecular Dynamics SimulationProtein StabilityQuantum TheorySongbirdsCryptochromesFree RadicalsSolvents

Identifiers

PMID41236751
PMCPMC12673606

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.