ReviewInternational dental journal2026
The Role and Progress of Antimicrobial Peptides in Managing Oral Biofilms: A Narrative Review.
Review in International dental journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Azithromycin in Dentistry: From Systemic Antibiotic to a Candidate for Local Therapeutic Delivery.Pharmaceutics · 2026Review
- Advances in Nanozyme Engineering for Precision Oral Health Management.International dental journal · 2026Review
- Editorial: Probiotics and bioactive agents in modulating harmful oral biofilms.Frontiers in microbiology · 2026Article
- Host-microbiome-immune disequilibrium in oral disease: mechanisms, dysbiosis, and precision therapeutics.Frontiers in immunology · 2026Review
- Antimicrobial Peptides as Novel Ecological Approaches to Caries Prevention.Drug design, development and therapy · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oral chronic infectious diseases are intrinsically linked to the formation of dental plaque biofilms, which significantly enhance bacterial resistance to antimicrobial agents and host defenses. The widespread misuse of antibiotics has further compounded this issue by selecting for drug-resistant microbial populations, complicating the clinical management of biofilm-associated oral diseases. Antimicrobial peptides (AMPs) have emerged as promising therapeutic agents due to their excellent biocompatibility, broad-spectrum antimicrobial activity, and low propensity for inducing bacterial resistance. This review aims to synthesise the role and latest progress of AMPs in combating oral biofilms, with a specific focus on their application potential against Cariogenic Biofilms, Periodontal Disease Biofilms, Root Canal Infection Biofilms, Peri-implantitis Biofilms, and Candida-associated biofilms. Furthermore, it summarises contemporary knowledge on AMP types, their mechanisms of biofilm inhibition, and advanced strategies for peptide modification and design, thereby bridging a critical gap in the current literature and providing essential insights for future AMP engineering and clinical translation.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.