Evidence map›Paper›PMID 41238572›Full record

ArticleBlood cancer journal2025

Combined MEK and JAK inhibition reduces osteopontin plasma level and bone marrow fibrosis in a myelofibrosis mouse model.

Lara Tavernari, Matteo Bertesi, Anita Neroni, Elisa Papa, Sebastiano Rontauroli, Elisa Bianchi, Margherita Mirabile, Ruggiero Norfo, Sandra Parenti, Camilla Tombari and 9 more

Abstract readLetter
In one paragraph

Article in Blood cancer journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Lara TavernariInterdepartmental Centre for Stem Cells and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy.ORCID http://orcid.org/0000-0002-4502-0895
Matteo BertesiInterdepartmental Centre for Stem Cells and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy.ORCID http://orcid.org/0000-0001-7896-5775
Anita NeroniInterdepartmental Centre for Stem Cells and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy.
Elisa PapaInterdepartmental Centre for Stem Cells and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy.ORCID http://orcid.org/0009-0005-0439-8532
Sebastiano RontauroliInterdepartmental Centre for Stem Cells and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy.
Elisa BianchiInterdepartmental Centre for Stem Cells and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy.ORCID http://orcid.org/0000-0002-6110-5944
Margherita MirabileInterdepartmental Centre for Stem Cells and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy.
Ruggiero NorfoInterdepartmental Centre for Stem Cells and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy.
Sandra ParentiInterdepartmental Centre for Stem Cells and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy.
Camilla TombariInterdepartmental Centre for Stem Cells and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy.
Chiara CarrettaInterdepartmental Centre for Stem Cells and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy.ORCID http://orcid.org/0000-0001-5952-0818
Marica MalerbaInterdepartmental Centre for Stem Cells and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy.ORCID http://orcid.org/0009-0003-4728-2164
Luca FabbianiPathology Unit, Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Paola GuglielmelliCRIMM, Center Research and Innovation of Myeloproliferative Neoplasms, University of Florence, AOU Careggi, Florence, Italy.ORCID http://orcid.org/0000-0003-1809-284X
Lorena LosiPathology Unit, Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Enrico TagliaficoDepartment of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Alessandro Maria VannucchiCRIMM, Center Research and Innovation of Myeloproliferative Neoplasms, University of Florence, AOU Careggi, Florence, Italy.
Rossella ManfrediniInterdepartmental Centre for Stem Cells and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy. rossella.manfredini@unimore.it.ORCID http://orcid.org/0000-0003-0660-6110
MYNERVA (MYeloid NEoplasms Research Venture AIRC) investigators

Funding

Associazione Italiana per la Ricerca sul Cancro (Italian Association for Cancer Research) 21267Associazione Italiana per la Ricerca sul Cancro (Italian Association for Cancer Research) 25829Associazione Italiana per la Ricerca sul Cancro (Italian Association for Cancer Research) 29077
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID41238572
PMCPMC12618570

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.