Evidence map›Paper›PMID 41238769›Full record

ReviewNature biomedical engineering2025

Barriers to translating continuous monitoring technologies for preventative medicine.

Jack Chen, Patricia Jastrzebska-Perfect, Peter Chai, Mehmet Girayhan Say, Jiaobing Tu, Wei Gao, Florencia Halperin, Joshua Korzenik, Hen-Wei Huang, Dina Katabi and 1 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Nature biomedical engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jack ChenDepartment of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Patricia Jastrzebska-PerfectDepartment of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, USA.
Peter ChaiDepartment of Emergency Medicine, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0003-0955-4117
Mehmet Girayhan SayDepartment of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Jiaobing TuAndrew and Peggy Cherng Department of Medical Engineering, California Institute of Technology, Pasadena, CA, USA.
Wei GaoAndrew and Peggy Cherng Department of Medical Engineering, California Institute of Technology, Pasadena, CA, USA.ORCID http://orcid.org/0000-0002-8503-4562
Florencia HalperinForm Health, Boston, MA, USA.
Joshua KorzenikDivision of Gastroenterology, Hepatology and Endoscopy, Department of Medicine, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, USA.
Hen-Wei HuangDivision of Gastroenterology, Hepatology and Endoscopy, Department of Medicine, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0003-1921-8897
Dina KatabiDepartment of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, USA.
Giovanni TraversoDepartment of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA. cgt20@mit.edu.ORCID http://orcid.org/0000-0001-7851-4077

Funding

Smart Steps: A context-aware adherence intervention to improve PrEP adherence among men who have sex with men (MSM) with substance use disorderDP2DA056107 · NIDA · BRIGHAM AND WOMEN'S HOSPITAL · PI CHAI, PETER R · 2022 to 2022
$2.7M
The ANTIDOTE Institute- Advancing New Toxicology Investigators in Drug abuse and Original Translational research EffortsR25DA058490 · NIDA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI STEPHANIE P CARREIRO, Peter R Chai · 2023 to 2026
$1.2M
NIDA NIH HHS DP2 DA056107NIDA NIH HHS R25 DA058490
6 · The paper itself

Abstract

While treatment remains essential, disease prevention often proves more effective in improving outcomes, enhancing well-being and reducing healthcare costs. Despite this understanding, preventative medical practices are still underutilized. Continuous monitoring technologies can help to address this gap by enabling early symptom detection, tracking disease recurrence and assessing treatment responses, yet few of the technologies have been integrated into clinical practice. In this Review, we discuss notable advances in continuous monitoring and the barriers to their translation. We focus on technologies that enable either continuous measurement for at least one week or periodic measurements for at least one month, including remotely interfacing technologies, wearables and other directly interfacing systems, and internally interfacing implanted devices. Continuous monitoring improves disease-risk assessment, tracks disease progression and enhances overall health management. However, broader and more reliable datasets from diverse clinical trials, alongside supportive policies and financial incentives, will be essential to overcoming translational barriers and to integrating these technologies into healthcare.

Indexed as

Preventive MedicineTranslational Research, BiomedicalHumansMonitoring, PhysiologicWearable Electronic Devices

Identifiers

PMID41238769
PMCPMC12639493

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.