Evidence map›Paper›PMID 41239350›Full record

ReviewCancer cell international2025

Immune checkpoint inhibitor-related arthritis and oral disorders: shared pathophysiology and clinical implications for rheumatology and oral health.

Mitra Abbasifard, Mobina Taghipoor, Mahsa Kimiae Talab, Hossein Khorramdelazad

Abstract readReview
In one paragraph

Review in Cancer cell international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mitra AbbasifardDepartment of Internal Medicine, Ali-Ibn Abi-Talib Hospital, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Mobina TaghipoorStudent Research Committee, School of DentistryShiraz University of Medical Sciences, Shiraz, Iran.
Mahsa Kimiae TalabDepartment of Oral and Maxillofacial Surgery, School of Dentistry, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Hossein KhorramdelazadDepartment of Immunology, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran. Khorramdelazad@Gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immune checkpoint inhibitors (ICIs) have revolutionized contemporary cancer treatment by enhancing anti-tumor immune responses and mitigating the suppressive effects of inhibitory molecules within the tumor microenvironment (TME). However, these immunotherapies may also induce immune-related adverse events (IrAEs), resulting in various disorders, including arthritis and oral diseases, which can negatively impact patients' quality of life and treatment outcomes. To effectively oversee ICI therapies and address immune dysregulation, it is essential to comprehend the interactions between these components. This review offers a comprehensive overview of ICI-induced arthritis and oral disorders, encompassing mechanisms, clinical presentation, diagnosis, and treatment strategies. Furthermore, it addresses emerging research pathways to improve clinical outcomes and patient care.

Indexed as

ArthritisCancer immunotherapyICI therapyOral diseases

Identifiers

PMID41239350
PMCPMC12619251

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.