ReviewJournal of ovarian research2025
Pathogenesis and treatment of obesity-related polycystic ovary syndrome.
Review in Journal of ovarian research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- The Hormonal-Metabolic Puzzle of PCOS: Linking AMH Levels, Body Fat Distribution, and Insulin Resistance in Overweight and Obese Women.Metabolites · 2026Article
- The immunogenetic basis of ovarian apoptosis: from TNF-α polymorphisms and signaling pathways to glucocorticoid-mediated rescue.Journal of ovarian research · 2026Review
- Modern Polycystic Ovary Syndrome (PCOS) Management: Intelligent Drug Delivery and Metabolic Reprogramming for Ovarian Restoration and Fertility Optimization.Biomolecules · 2026Review
- Interconnected cell death pathways: central mechanisms and therapeutic targets in impaired follicular development of polycystic ovary syndrome.Journal of ovarian research · 2026Review
- Genistein in polycystic ovary syndrome: mechanisms, preclinical evidence, and translational potential.Frontiers in global women's health · 2026Review
- Sleep Disruption and Shift Work Associate with Increased Risk of Reproductive Endocrine Disorders: Evidence from UK Biobank and Mendelian Randomization.International journal of women's health · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Polycystic ovary syndrome (PCOS) is a gynecological endocrine disorder affecting 5%-18% of women of reproductive age worldwide. It is characterized by hyperandrogenemia (HA), anovulation, and polycystic ovarian morphology (PCOM), severely impacting women's reproductive and metabolic health. Obesity has become increasingly common among PCOS patients in recent years. Obesity can further exacerbate the metabolic and reproductive dysfunctions of PCOS through mechanisms such as insulin resistance (IR) and chronic low-grade inflammation. It may even have adverse effects on mental health. However, the specific pathogenesis and effective therapeutic targets of PCOS with obesity remain incompletely understood. This review presents a narrative review of recent research, focusing on the molecular mechanisms that drive autophagy in the context of obesity associated with polycystic ovary syndrome (PCOS), endoplasmic reticulum stress (ERS), gut microbiota imbalances, and disruptions in the hypothalamic-pituitary-ovarian (HPO) axis. It also explores corresponding therapeutic strategies. The aim is to provide fresh perspectives and insights for future mechanistic research and clinical interventions in this field.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.