Evidence map›Paper›PMID 41239550›Full record

ArticlePhysiological reports2025

Acute live firefighting effects on ventricular-arterial coupling and pulsatile afterload in middle-aged firefighters.

João L Marôco, Abbi D Lane, Sushant M Ranadive, Huimin Yan, Kanokwan Bunsawat, Gavin P Horn, Denise L Smith, Tracy Baynard, Bo Fernhall

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physiological reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

João L MarôcoIntegrative Human Physiology Laboratory, Manning College of Nursing & Health Sciences, University of Massachusetts Boston, Boston, Massachusetts, USA.ORCID 0000-0002-5691-5272
Abbi D LaneSchool of Kinesiology, University of Michigan, Ann Arbor, Michigan, USA.
Sushant M RanadiveDepartment of Kinesiology, School of Public Health, University of Maryland, College Park, Maryland, USA.
Huimin YanDepartment of Exercise and Health Sciences, University of Massachusetts Boston, Boston, Massachusetts, USA.
Kanokwan BunsawatDivision of Geriatrics, Department of Internal Medicine, University of Utah, Salt Lake City, Utah, USA.
Gavin P HornFire Safety Research Institute, UL Research Institutes, Columbia, Maryland, USA.
Denise L SmithIllinois Fire Service Institute, University of Illinois-Urbana/Champaign, Champaign, Illinois, USA.
Tracy BaynardIntegrative Human Physiology Laboratory, Manning College of Nursing & Health Sciences, University of Massachusetts Boston, Boston, Massachusetts, USA.
Bo FernhallIntegrative Human Physiology Laboratory, Manning College of Nursing & Health Sciences, University of Massachusetts Boston, Boston, Massachusetts, USA.ORCID 0000-0001-9393-3018

Funding

U.S. Department of Homeland Security (DHS) EMW-2009-FP-00544
6 · The paper itself

Abstract

Firefighting increases afterload, leading to ventricular-arterial coupling mismatch in young firefighters that may contribute to coronary hypoperfusion and the elevated risk of on-duty cardiac events. Since this risk is higher with aging in firefighters, we examined their ventricular-vascular coupling and afterload responses to acute firefighting. Twenty-two male firefighters (40-59 years) performed 18-min high-intensity firefighting drills while wearing protective gear and breathing apparatus. Echocardiography was conducted before and within 10 min after firefighting to estimate cardiac volumes, while tonometry-derived pulse wave analysis estimated wasted pressure effort (Ew) and aortic reservoir function. Ventricular-arterial coupling was quantified using the arterial (Ea) to ventricular (Ees) elastance ratio, and coronary perfusion was estimated via the Buckberg index. Firefighting reduced stroke volume (difference (∆) = -17 mL, p < 0.001), Ew (∆ = -800 dyne cm

Indexed as

FirefightersAdultCoronary CirculationHumansMaleMiddle AgedPulsatile FlowPulse Wave AnalysisStroke Volumearterial elastanceheart vascular interactionsventricular elastance

Identifiers

PMID41239550
PMCPMC12618204

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.