Evidence map›Paper›PMID 41240109›Full record

ArticleInternational urogynecology journal2026

Oxidative Balance Score and Overactive Bladder Risk in US Adults: A Negative Dose-Response Association from NHANES 2005-2018.

Di Ma, Xinyue Wang, Yilan Li, Xiaoqin Luo

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Article in International urogynecology journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Di MaDepartment of Nutrition and Food Safety, School of Public Health, Xi'an Jiaotong University, Xi'an, 710061, China.
Xinyue WangDepartment of Nutrition and Food Safety, School of Public Health, Xi'an Jiaotong University, Xi'an, 710061, China.
Yilan LiDepartment of Nutrition and Food Safety, School of Public Health, Xi'an Jiaotong University, Xi'an, 710061, China.
Xiaoqin LuoDepartment of Nutrition and Food Safety, School of Public Health, Xi'an Jiaotong University, Xi'an, 710061, China. luoxiaoqin2012@mail.xjtu.edu.cn.ORCID 0000-0002-3572-3909

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction and hypothesisEvidence suggests that oxidative stress might play a key role in the pathogenesis of overactive bladder (OAB). However, the association between oxidative balance scores (OBS) and OAB risk remains unclear. This study was aimed at exploring the potential dose-response association between OBS and OAB.

methodsThe data were obtained from the National Health and Nutrition Examination Survey database from 2005 to 2018. OAB was defined as the presence of urge urinary incontinence and nocturia, with a modified overactive bladder symptom score ≥ 3, according to the International Continence Society. A higher OAB score indicates more severe symptoms. OBS was scored by 20 dietary and lifestyle factors, with a higher OBS indicating higher antioxidant status. Associations between OBS and OAB were investigated using multivariate logistic regression, subgroup analysis, and smoothed curve fitting.

resultsA total of 26,695 individuals were included in this study, with an OAB prevalence of 19.9%. A higher level of OBS was significantly associated with a reduced risk of OAB. After adjusting for potential variables, compared with the first tertile (T1) of OBS, the risk of OAB in the third tertile (T3) decreased by 12% (OR = 0.88, 95% CI: 0.80-0.97). The smoothing curve fitting showed that a negative and nearly linear correlation between OBS and OAB risk (p for nonlinearity: 0.172). This association remained stable across different subgroups.

conclusionsThis study identified a negative linear association between OBS and OAB in the USA.

Indexed as

Oxidative StressUrinary Bladder, OveractiveAdultAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedNutrition SurveysPrevalenceRisk FactorsUnited StatesLogistic regressionNational Health and Nutrition Examination SurveyOveractive bladderOxidative balance score

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.