Evidence map›Paper›PMID 41240137›Full record

ArticleVeterinary research communications2025

Brain metastases from endometrial carcinoma in two dogs.

Isabelle Vieira de Sousa, Daniela Dantas de Gois, Francisca Maria Sousa Barbosa, Carla Manuela Morais Pinto, Raquel Annes Fagundes Silva, Ricardo Barbosa Lucena

Abstract readCase Reports
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In one paragraph

Article in Veterinary research communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Isabelle Vieira de SousaGraduate Program in Animal Health and Science, Center for Rural Health and Technology, Universidade Federal de Campina Grande, Patos, Paraiba, 58708-110, Brazil.ORCID http://orcid.org/0000-0002-6133-8828
Daniela Dantas de GoisPathobiology Laboratory, Graduate Program in Animal and Science, Agricultural Sciences Center, Universidade Federal da Paraiba, Areia, Paraiba, 58397-000, Brazil.ORCID http://orcid.org/0000-0003-3213-0507
Francisca Maria Sousa BarbosaPathobiology Laboratory, Graduate Program in Animal and Science, Agricultural Sciences Center, Universidade Federal da Paraiba, Areia, Paraiba, 58397-000, Brazil.ORCID http://orcid.org/0000-0002-9058-9298
Carla Manuela Morais PintoPathobiology Laboratory, Graduate Program in Animal and Science, Agricultural Sciences Center, Universidade Federal da Paraiba, Areia, Paraiba, 58397-000, Brazil.ORCID http://orcid.org/0009-0001-5951-4407
Raquel Annes Fagundes SilvaGraduate Program in Animal Health and Science, Center for Rural Health and Technology, Universidade Federal de Campina Grande, Patos, Paraiba, 58708-110, Brazil.ORCID http://orcid.org/0000-0001-5847-6931
Ricardo Barbosa LucenaGraduate Program in Animal Health and Science, Center for Rural Health and Technology, Universidade Federal de Campina Grande, Patos, Paraiba, 58708-110, Brazil. ricardolucena@cca.ufpb.br.ORCID http://orcid.org/0000-0002-2968-5766

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Finance Code 001
6 · The paper itself

Abstract

Endometrial carcinoma is an uncommon epithelial neoplasm in dogs. This study reports two cases of endometrial carcinomas with brain metastasis in a 7-year-old mixed-breed dog with bloody vulvar discharge, prostration, lethargy, and hyperextension of all four limbs, and an 11-year-old Poodle with purulent vulvar discharge, dyspnea, lateral recumbency, limb stiffness, and epistaxis. Both dogs died during emergency care. Necropsy revealed multiple metastatic nodules in several organs, including the brain. Histopathology showed proliferative endometrial glands with atypical cuboidal-to-columnar cells, while immunohistochemistry confirmed epithelial origin (AE1/AE3-positive). These findings underscore the importance of including endometrial carcinoma in the differential diagnosis of disseminated metastatic disease associated with acute neurological conditions in dogs.

Indexed as

Brain NeoplasmsCarcinomaDog DiseasesEndometrial NeoplasmsAnimalsDogsFatal OutcomeFemaleCanineImmunohistochemistryNeoplasiaUterine carcinoma

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.