ArticleBiological trace element research2026
Lead-induced Hepatotoxicity in Rat Hepatocytes: a Transcriptomic Network Analysis Reveals Key Molecular Insights.
Article in Biological trace element research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Ameliorative Role of fenugreek Oil Against Lead Acetate Trihydrate-Induced Hepatic, Renal and Testicular Injury in Wistar Albino Rats: Insights into Bcl-2 Expression and sodium/potassium balance.Biological trace element research · 2026Article
- Article
- Decoding the hub gene blueprint for broiler liver development: A synergistic histomorphological and transcriptomic investigation during the neonatal phase.Poultry science · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lead (Pb), a ubiquitous environmental pollutant, poses significant hepatotoxic risks in mammalian systems. Despite its widespread exposure, the precise molecular mechanisms driving Pb-induced liver injury remain incompletely understood. This investigation employed a systems biology approach to delineate critical molecular networks and hub genes mediating Pb hepatotoxicity through integrative analysis of GEO hepatotoxicity datasets. Transcriptomic profiling of rat primary hepatocytes (RPHCs) exposed to 10 ppm Pb(NO3)
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.