SynthesisAdvances in nutrition (Bethesda, Md.)2025
Adherence to Mediterranean Diet and Risk of Type 2 Diabetes: An Updated Systematic Review and Dose-Response Meta-analysis.
Synthesis in Advances in nutrition (Bethesda, Md.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Plant-Based Nutrition and Type 2 Diabetes Mellitus: Prevention, Risk, Metabolic Health and the Role of Legumes, Dietary Fiber, and Red Meat.Nutrients · 2026Review
- Observational
- Insulin Resistance as a Systemic Metabolic Risk State for Cancer: Mechanisms, Biomarkers, and Prevention.International journal of molecular sciences · 2026Review
- Mediterranean Dietary Pattern in Type 2 Diabetes Management: Pathways and Clinical Evidence.Biomedicines · 2026Review
- Mediterranean Lifestyle Adherence Reflects Coherent Behavioural Patterns Based on the MEDLIFE Index.Nutrients · 2026Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGiven the global rise in type 2 diabetes mellitus (T2D), the Mediterranean diet (MedDiet) has gained attention as a promising preventive dietary pattern.
objectivesThis study aims to update and extend our previous systematic review by synthesizing current evidence from randomized controlled trials (RCTs) and prospective cohort studies on the association between MedDiet adherence and incident T2D in adults, and to evaluate the certainty of evidence.
methodsWe conducted a systematic search in MEDLINE, Cochrane CENTRAL, and Scopus from 2014 to May 2025. Eligible studies were prospective cohorts reporting on the adherence to an a priori-defined MedDiet or, for RCTs, MedDiet intervention compared with any other diet and T2D incidence. Random-effects dose-response meta-analyses were performed to estimate hazard ratios (HRs) for MedDiet adherence score. Risk of bias was assessed using the Cochrane risk of bias tool 2 and the Risk Of Bias In Nonrandomized Studies-of Exposures tool, and the certainty of evidence was rated using the Grading of Recommendations Assessment, Development and Evaluation approach.
resultsA total of 24 prospective cohort studies and 1 RCT were included, comprising 991,878 participants and 68,325 T2D cases and a mean follow-up duration of 12.2 y (range: 3.5- 25 y). Higher MedDiet adherence is likely associated with a reduced risk of T2D [HR
conclusionThis updated systematic review and meta-analysis provides moderate-certainty evidence that greater adherence to the MedDiet is associated with a lower risk of T2D. These findings reinforce current dietary guidelines recommending MedDiet as a sound strategy for T2D prevention.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.