Evidence map›Paper›PMID 41243363›Full record

Trial reportThe Journal of physiology2026

Isolating the effects of carbohydrate and lipid availability on exercise-induced skeletal muscle signalling in males.

Louise Bradshaw, Alfonso Moreno Cabañas, Bruno Spellanzon, Katie Marie Hutchins, Adam J Collins, Jariya Buniam, Thibaux van der Stede, Joanne Mallinson, Kostas Tsintzas, Wim Derave and 4 more

Erratum issuedAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The Journal of physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Louise BradshawCentre for Nutrition, Exercise and Metabolism, University of Bath, Bath, UK.
Alfonso Moreno CabañasCentre for Nutrition, Exercise and Metabolism, University of Bath, Bath, UK.
Bruno SpellanzonCentre for Nutrition, Exercise and Metabolism, University of Bath, Bath, UK.
Katie Marie HutchinsCentre for Nutrition, Exercise and Metabolism, University of Bath, Bath, UK.
Adam J CollinsCentre for Nutrition, Exercise and Metabolism, University of Bath, Bath, UK.
Jariya BuniamCentre for Nutrition, Exercise and Metabolism, University of Bath, Bath, UK.
Thibaux van der StedeDepartment of Movement and Sport Sciences, Ghent University, Ghent, Belgium.
Joanne MallinsonMRC Versus Arthritis Centre for Musculoskeletal Ageing Research, School of Life Sciences, University of Nottingham, Queen's Medical Centre, Nottingham, UK.
Kostas TsintzasMRC Versus Arthritis Centre for Musculoskeletal Ageing Research, School of Life Sciences, University of Nottingham, Queen's Medical Centre, Nottingham, UK.
Wim DeraveDepartment of Movement and Sport Sciences, Ghent University, Ghent, Belgium.
Jean-Philippe WalhinCentre for Nutrition, Exercise and Metabolism, University of Bath, Bath, UK.
James A BettsCentre for Nutrition, Exercise and Metabolism, University of Bath, Bath, UK.
Francoise KoumanovCentre for Nutrition, Exercise and Metabolism, University of Bath, Bath, UK.
Javier T GonzalezCentre for Nutrition, Exercise and Metabolism, University of Bath, Bath, UK.ORCID 0000-0002-9939-0074

Funding

University of Bath
6 · The paper itself

Abstract

Training with low carbohydrate availability can increase AMP-activated protein kinase (AMPK) activation, but whether increased AMPK activation is the result of low carbohydrate availability per se or concurrent increases in fatty acid availability/oxidation is unclear. This study assessed the independent effects of carbohydrate and fatty acid availability on exercise-induced skeletal muscle AMPK activation and downstream signalling. Eight active males who were aged between 18 and 60 years with a body mass index in the range 18.0-30.0 kg m

Indexed as

Dietary CarbohydratesExerciseLipid MetabolismMuscle, SkeletalAcetyl-CoA CarboxylaseAdolescentAdultAMP-Activated Protein KinasesCross-Over StudiesFatty Acids, NonesterifiedGlycogenHumansInsulinMaleMiddle AgedNiacinAcetyl-CoA CarboxylaseAMP-Activated Protein KinasesDietary CarbohydratesFatty Acids, NonesterifiedGlycogenInsulinNiacincarbohydrate metabolismcell signallingexercise metabolismlipid metabolism

Identifiers

PMID41243363
PMCPMC12783980

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.