Evidence map›Paper›PMID 41244005›Full record

ArticleMedComm2025

Incidence, Risk Factors, and Epidemiological Trends of Head and Neck Cancer: A Global Analysis.

Junjie Huang, Shui Hang Chow MSocSc, Mingtao Chen MSocSc, Sze Chai Chan, Jinqiu Yuan, Lin Zhang, Claire Chenwen Zhong, Wanghong Xu, Zhi-Jie Zheng, Zigui Chen and 2 more

Abstract read
In one paragraph

Article in MedComm, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Timing matters: concurrentTranslational cancer research · 2026
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Junjie HuangThe Jockey Club School of Public Health and Primary Care, Faculty of Medicine Chinese University of Hong Kong Hong Kong China.
Shui Hang Chow MSocScThe Jockey Club School of Public Health and Primary Care, Faculty of Medicine Chinese University of Hong Kong Hong Kong China.
Mingtao Chen MSocScThe Jockey Club School of Public Health and Primary Care, Faculty of Medicine Chinese University of Hong Kong Hong Kong China.
Sze Chai ChanThe Jockey Club School of Public Health and Primary Care, Faculty of Medicine Chinese University of Hong Kong Hong Kong China.
Jinqiu YuanClinical Research Center, Big Data Center, The Seventh Affiliated Hospital Sun Yat-Sen University Shenzhen Guangdong China.
Lin ZhangThe School of Public Health and Preventive Medicine Monash University Victoria Australia.
Claire Chenwen ZhongThe Jockey Club School of Public Health and Primary Care, Faculty of Medicine Chinese University of Hong Kong Hong Kong China.
Wanghong XuSchool of Public Health Fudan University Shanghai China.
Zhi-Jie ZhengDepartment of Global Health, School of Public Health Peking University Beijing China.
Zigui ChenDepartment of Microbiology, Faculty of Medicine The Chinese University of Hong Kong Hong Kong China.
Jason Y K ChanDepartment of Otorhinolaryngology, Head and Neck Surgery, Faculty of Medicine The Chinese University of Hong Kong Hong Kong China.
Martin C S WongThe Jockey Club School of Public Health and Primary Care, Faculty of Medicine Chinese University of Hong Kong Hong Kong China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Head and neck cancer (HNC) is a type of common cancer accounting for approximately 4.7% of all incident cancer cases in 2022. This study aims to investigate the trend of HNC on global distribution. We collected related data from the Global Cancer Observatory and Cancer Incidence in Five Continents Plus database, risk factor data at the country level, HDI, and GDP. Multivariable linear regression was conducted to assess HNC and risk factors. Joinpoint regression analysis was used to calculate Average Annual Percentage Change (AAPC). The global age-standardized rate of HNC incidence was 9.8 in 2022. At the sub-region level, Melanesia (18.5), South Central Asia (16.2), and Eastern Europe (12.7) had the highest incidence of HNC. At the country level, Bangladesh (23.7) and Papua New Guinea (22.2) had the highest incidence. A higher HNC incidence ratio was associated with higher levels of smoking, alcohol drinking, unhealthy dietary behavior, diabetes, and lipid disorders. There was a rising trend in HNC for the female population, which may be attributed to the increase in female smoking. Mixed trends were observed in the male population, with decreasing trends observed in some high-HDI countries where smoking is better controlled. Future studies are recommended to investigate the epidemiological changes.

Indexed as

distributionhead and neck cancerrisk factorstemporal trends

Identifiers

PMID41244005
PMCPMC12616870

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.